Peptides for the treatment of Alzheimer's disease and other...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C514S002600, C424S185100, C424S184100, C530S300000, C530S326000

Reexamination Certificate

active

10933206

ABSTRACT:
A pharmaceutical composition comprising peptide HA3G76 Tyr-Leu-Ser-Lys-Gly-Arg-Leu-Val-Phe-Ala-Leu-Gly (SEQ ID NO:8).

REFERENCES:
Koo et al. “Amyloid β-Protein as a Substrate Interacts with Extracellular Matrix to Promote Neurite Outgrowth,” Proc. Natl. Acad. Science, vol. 90, pp. 4748-4752, May 1993.
Narindrasorsak et al. “Characterization of High Affinity Binding between Laminin and Alzheimer's Disease Amyloid Precursor Proteins,” Laboratory Investigation, vol. 67, No. 5, pp. 643-652, 1992.
Narindrasorsak et al. “An Interaction between Basement Membrane and Alzheimer Amyloid Precursor Proteins Suggests a Role in the Pathogenesis of Alzheimer's Disease,” Laboratory Investigation, vol. 72, No. 3, pp. 272-282, 1995.
Mann. “Cerebral Amyloidosis, Ageing and Alzheimer's Disease; A Contribution From Studies on Down's Syndrome,” Neurobiology of Aging, vol. 10, pp. 397-399, 1989.
Gajdusek. “Unconventional viruses and the Origen and Disappearance of Kuru,” Science, vol. 197, No. 4307, Sep. 2, 1977.
Prusiner et al. “Purification and Structural Studies of a Major Scrapie Prion Protein,” Cell, vol. 38, 127-134, Aug. 1984.
Prusiner. “Prions,” [publication data unknown].
Tateishi et al. “Gerstmann-Straussler-Scheinker Disease: Immunohistological and Experimental Studies,” Annals of Nuerology, vol. 24, No. 1, Jul. 1988.
Foidart et al. “Distribution and Immunoelectron Microscopic Localization of Laminin, A Non collagenous Basement Membrane Glycoprotein,” Laboratory Investigation, vol. 42, No. 3, p. 336, 1980.
Burgeson et al. “A New Nomenclature for the Laminins,” Matrix Biology, vol. 14, pp. 209-211, 1994.
Yurchenco et al. “Laminin Polymerization in Vitro: Evidence for a two step assembly with Domain Specificity,” The Journal of Biological Chemistry, vol. 260, No. 12, pp. 7636-7644, Jun. 25, 1985.
Yurchenco et al. “Laminin Forms an Independent Network in Basement Membranes,” The journal of Cell Biology, vol. 117, No. 5, pp. 1119-1133, Jun. 1993.
Newgreen et al. “Fibronectin in Early Avian Embryos: Synthesis and Distribution Along the Migration Pathways of Neural Crest Cells,” Cell tissue res. vol. 211, pp. 211-269, 1980.
Rovasio et al. “Neural Crest Cell Migration: Requirements for Exogenous Fibronectin and High Cell Density,” The Journal of Cell Biology, vol. 96, pp. 462-473, Feb. 1983.
Lander et al. “Laminin is associated with the ‘nuerite outgrowth-promotion factors’ found in conditioned media,” Proc. Natl. Acad. Sci. USA , vol. 82, pp. 2183-2187, Apr. 1985.
Fraser et al. “A monoclonal antibody against a laminin-heparan sulfate proteoglycan complex perturbs cranial neural crest migration in vivo,” The Journal of Cell Biology, vol. 106, pp. 1321-1329, Apr. 1988.
Kleinman et al. “Formation of a Supramolecular Complex Is Involved the Reconstitution of Basement Membrane Composets,” Biochemistry, vol. 22, pp. 4969-4974, 1983.
Engvall et al. “Mapping of Domains in Human Laminin Using Monoclonal Antibodies: Localization of the Neurite-promotion Site,” The Journal of Cell Biology, vol. 103, No. 6, Pt. 1, pp. 2457-2465, 1986.
Liesi et al. “Laminin is induced in astrocytes of adult brain by injury,” The EMBO Journal, vol. 3, No. 3, pp. 683-686, 1984.
Terranova et al. “Role of laminin in the attachment of PAM 212 (epithelial) Cells to Basement Membrane Collagen,” Cell, vol. 22, pp. 719-726, Dec. 1980.
Rao et al. “Binding domain for laminin of type IV collagen,” Biochemical and biophysical research communications, vol. 128, No. 1, Apr. 16, 1985.
Charonis et al. “Binding of laminin to type IV collagen: A morphological study,” The Journal of Cell Biology, vol. 100, pp. 1848-1853, 1985.
Laurie et al. “Localization of Binding Sites for Laminin, Heparan Sulfate Proteoglycan and Fibronectin on Basement Membrane (Tyoe IV) Collagen,” J. Mol. Biol., vol. 189, pp. 205-216, 1986.
Riopelle et al. Functional interactions of neuronal heparan sulphate preoteoglycans with laminin, Brain Research, vol. 525, pp. 92-100, 1990.
Battaglia et al. “Basement-membrane heparan sulfate proteoglycan binds to laminin by its heparan sulfate chains and to nidogen by sites in the protein core,” Eur. J. Biochem., vol. 208, pp. 359-366, 1992.
Sakashita et al. “Basement membrane glycoprotein laminin binds to heparin,” FEBS letters, vol. 116, No. 2, Jul. 1980.
Del Rosso et al. “Binding of the basement-membrane glycoprotein laminin to glycosaminoglycans,” Biochem. J., vol. 199, pp. 699-704, 1981.
Skubitz et al. “Localization of three distinct heparin-hinding Domains of Laminin by Monoclonal antibodies,” The Journal of biological chemistry, vol. 263, No. 10, pp. 4861-4868, Apr. 5, 1988.
Hall et al. “The α1/β1and α1/β1integrin heterodimers mediate cell attachment to distinct sites on laminin,” The Journal of Cell Biology, vol. 110, pp. 2175-2184, Jun. 1990.
Goodman et al; “Multiple cell surface receptors for the short arms of laminin: α1/β1 integrin and RGD-dependent proteins mediate cell attachment only to domains III in Murine Tumor Laminin,” The Journal of Cell Biology, vol. 113, No. 4, pp. 931-941, May 1991.
Yurchenco et al. “Heparin modulation of laminin polymerization,” The Journal of Biological chemistry, vol. 265, No. 7, pp. 3981-3991, Mar. 5, 1990.
Fox et al. “Recombinant nidogen consists of three globular domains and mediates binding of laminin to collagen type IV,” The EMBO Journal, vol. 10, No. 11, pp. 3137-3146, 1991.
Sung et al. “Cell and Heparin Binding in the Distal Long Arm of Laminin: Identification of Active and Cryptic Sites with Recombinant and Hybrid Glycoprotein,” The Journal of Cell Biology, vol. 123, No. 5, pp. 1255-1268, Dec. 1993.
Shimomura et al. “Studies on Macromolecular Components of human glomerular basement membrane and alterations in diabetes,” Diabetes. vol. 36, Mar. 1987.
Lyon et al. “Co-deposition of basement membrane components during the induction of murine splenic AA amyloid,” Laboratory investigation, vol. 64, No. 6, p. 785, 1991.
Perlmutter et al. “Microangiopathy, the Vascular Basement Membrane and Alzheimer's Disease: A Review,” Brain Research Bulletin, vol. 24, pp. 677-686, 1990.
Murtomaki et al. “Laminin and its neurite outgrowth-promotin domain in the brain in alzheimer's disease and down's syndrome patients,” Jounal of Neuroscience Research, vol. 32, pp. 261-273, 1992.
Perlimutter et al. “Vascular basement membrane components and the lesions of Alzheimer's Disease: light and electron microscopic analyses,” Microscopy research and technique, vol. 28, pp. 204-215, 1994.
Narindrasorasak et al. “Characterization of high affinity binding between lanimim and Alzheimer's Disease amyloid precursor proteins,” Laboratory investigation, vol. 67, No. 5, p. 643, 1992.
Naiki et al. “Kinetic analysis of amyloid fibril polymerization in vitro,” Laboratory investigation, vol. 65, No. 1, p. 104, 1991.
Levine et al. “Thioflavine T interaction with synthetic Alzheimer's Disease β-amyloid peptides: detection of amyloid aggregation in solution,” Protein Science, vol. 2, pp. 404-410, 1993.
Maiki et al. “First-order kinetic model of Alzheimer's β-amyloid fibril extension in vitro,” Laboratory investigation, vol. 74, No. 2, p. 374, 1996.
Westermark et al. “Islet amyloid in type 2 human diabetes mellitus and adult diabitic ats cantains a novel putative polypeptide hormone,” American Journal of Pathology, vol. 127, No. 3, Jun. 1987.
Cooper et al. “Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabitic patients,” Proc. N

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