Peptides for the detection of HIV-1 group O

Details Peptides for the detection of HIV-1 group O Peptides for the detection of HIV-1 group O

1999-11-04

2000-11-21

Stucker, Jeffrey

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

4241841, 4241851, 4241861, 4242041, 4242081, 530324, 530300, A61K 3921, A61K 3900, A61K 3938, A61K 3912, A61K 3800

Patent

active

061499102

ABSTRACT:
This invention relates to peptides and their preparation. The peptides each have a sequence that corresponds to the immunodominant region of the HIV-1 group O gp41 envelope protein. The sequence is characterized in that it does not correspond to any known naturally occurring group O sequence or variant. Furthermore, the peptide binds anti-HIV-1 group O antibodies. There are several uses for the peptides, including the detection of antibodies produced in response to HIV-1 group O infection. The peptides may also be incorporated in mosaics and expressed recombinantly.

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