Peptides for recognition and targeting of GLIAL cell tumors

Details Peptides for recognition and targeting of GLIAL cell tumors Peptides for recognition and targeting of GLIAL cell tumors

2006-08-22

2006-08-22

Helms, Larry R. (Department: 1643)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

8 to 10 amino acid residues in defined sequence

C530S300000, C530S329000, C530S330000, C530S333000, C435S005000, C435S007230, C435S235100, C435S320100

Reexamination Certificate

active

07094868

ABSTRACT:
Compositions for use in characterization, diagnosis, prognosis, and therapy of cancer cells are provided. The compositions comprise peptides and variants thereof which were isolated based on their ability to selectively bind glioma cells.

REFERENCES:
patent: 6395873 (2002-05-01), Pierschbacher et al.
patent: 6551795 (2003-04-01), Rubenfield et al.
patent: WO 9957149 (1999-11-01), None
patent: WO 200122922 (2001-04-01), None
patent: WO 200124810 (2001-04-01), None
Zhang et al. Cancer Letters, 171(2):153-164, Oct. 10, 2001.
Koivunen et al. Biotechnology, 13(3):265-270, Mar. 1995.
Samoylova et al. Molecular Cancer Therapeutics, 2:1129-1137, 2003.
Samoylova T. I., et al. “Targeting Peptides for Microglia Identified via Phage Display,” Journal of Neuroimmunology, 2002, pp. 13-21, vol. 127(1-2).
Akiyama, S., “Integrins in Cell Adhesion and Signaling,”Human Cell, 1996, pp. 181-186, vol. 9(3).
Bafetti et al., “Intact Vitronectin Induces Matrix Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinases-2 Expression and Enhanced Cellular Invasion by Melanoma Cells,”The Journal of Biological Chemistry, 1998, pp. 143-149, vol. 273(1).
Barry, et al., “Toward Cell-Targeting Gene Therapy Vectors: Selection of Cell-Binding Peptides from Random Peptide-Presenting Phage Libraries,”Nature Medicine, 1996, pp. 299-305, vol. 2(3).
Ruoslahti, E., “Integrins as Signaling Molecules and Targets for Tumor Therapy,”Kidney International, 1997, pp. 1413-1417, vol. 51.
Zamir, et al., “Molecular Complexity and Dynamics of Cell-Matrix Adhesions,”Journal of Cell Science, 2001, pp. 3583-3590, vol. 114.
Romanov, V.I., et al., “Phage Display Selection of Peptides That Affect Prostate Carcinoma Cells Attachment and Invasion,”Prostate, 2003, pp. 239-251, vol. 47(4).
Samoylova, T.I., et al., “Targeting Peptides for Microglia Identified Via Phage Display,” 2002, pp. 13-21. vol. 127(1-2).
Samoylova, T.I., et al., “Molecular Markers of Glial Tumors: Current Tarteting Strategies,”Curr. Med. Chem., 2003, pp. 831-843, vol. 10(10).
Gehlsen, K.R., et al., “Inhibition of In Vitro Tumor Cell Invasion byArg-Gly-Asp-containing Synthetic Peptides,”The Journal of Cell Biology, Mar. 1988, pp. 925-930, vol. 106.

Affiliated with

Also associated with

Rating

Peptides for recognition and targeting of GLIAL cell tumors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Peptides for recognition and targeting of GLIAL cell tumors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptides for recognition and targeting of GLIAL cell tumors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3648432