Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2006-09-26
2006-09-26
Priebe, Scott D. (Department: 1632)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S006120, C435S320100, C530S300000, C530S324000, C530S325000, C530S326000, C530S327000, C530S328000, C530S329000, 53, 53
Reexamination Certificate
active
07112442
ABSTRACT:
Compositions and methods are described for nucleic acid formulation for gene delivery. A new class of low molecular weight condensing agents, namely aromatic amino acid—containing peptides, are described for use in receptor-mediated and nonreceptor-mediated gene delivery, both in vivo and in vitro.
REFERENCES:
patent: 5166320 (1992-11-01), Wu et al.
patent: 5270300 (1993-12-01), Hunziker
patent: 5298422 (1994-03-01), Schwartz et al.
patent: 5304121 (1994-04-01), Sahatjian
patent: 5324775 (1994-06-01), Rhee et al.
patent: 5354844 (1994-10-01), Beug et al.
patent: 5460831 (1995-10-01), Kossovsky et al.
patent: 5464650 (1995-11-01), Berg et al.
patent: 5470829 (1995-11-01), Prisell et al.
patent: 5545135 (1996-08-01), Iacob et al.
patent: 5580859 (1996-12-01), Felgner et al.
patent: 5593974 (1997-01-01), Rosenberg et al.
patent: 5635383 (1997-06-01), Wu et al.
patent: 5674192 (1997-10-01), Sahatjian et al.
patent: 5674703 (1997-10-01), Woo et al.
patent: 5693622 (1997-12-01), Wolff et al.
patent: 5698531 (1997-12-01), Nabel et al.
patent: 5707969 (1998-01-01), Nabel et al.
patent: 5723119 (1998-03-01), Schwartz et al.
patent: 5736392 (1998-04-01), Hawley-Nelson et al.
patent: 5763416 (1998-06-01), Bonadio et al.
patent: 5770580 (1998-06-01), Ledley et al.
patent: 5874297 (1999-02-01), Wu et al.
patent: 5879713 (1999-03-01), Roth et al.
patent: 6387700 (2002-05-01), Rice et al.
patent: 6770740 (2004-08-01), Rice et al.
patent: 0 190 833 (1986-08-01), None
patent: WO 90/11092 (1990-10-01), None
patent: WO9 3/21969 (1993-11-01), None
patent: WO 95/24929 (1995-09-01), None
patent: WO 96/20698 (1996-07-01), None
patent: WO 97/38729 (1997-10-01), None
patent: WO 97/46100 (1997-12-01), None
patent: WO 97/47254 (1997-12-01), None
patent: WO 98/19711 (1998-05-01), None
Mountain, A., “Gene therapy: the first decade,” Trends in Biotechnology 18: 119-128, Mar. 2000.
Verma et al., “Gene therapy—promises, problems, and prospects,” Nature 389: 239-242, Sep. 18, 1997.
Orkin et al., Report and Recommendations of the Panel to Assess the NIH Investment in Research on Gene Therapy, issued by the U.S. National Institutes of Health, Dec. 7, 1995.
Boulikas and Martin, “Histones, Protamine, and Polylysine but not Poly(E:K) Enhance Transfection Efficiency,”International Journal of Oncology, 10(2):317-322, 1997, abstract only.
Eisen, et al., “Enhanced Efficiency ofIn VivoGene Transfer into the Thymus in Rats Using Polylysine-Folate Transfection Vectors,”Clin. Res., 42(3), 443A, 1994.
Schulz and Schirmer, “Principles of Protein Structure,”Springer-Verlag New York, pp. 12-13, 1979.
Wadhwa et al., “Peptide-Mediated Gene Delivery: Influence of Peptide Structure on Gene Expression,”Bioconjugate Chem., 8:81-88, 1997.
Williams, et al., “The Primary Structure of Hen Ovotransferrin,”Eur. J. Biochem., 122:297-303, 1982.
Official Action for parent U.S. Appl. No. 08/743,269, filed, Nov., 4, 1996.
International Search Report for PCT/US97/19621, mailed Jan., 30, 1998.
Fang et al., “Stimulation of New Bone Formation by Direct Transfer of Osteogenic Plasmid Genes,”Proc. Natl. Acad. Sci. USA, 93:5753-5758, 1996.
International Search Report for PCT/US99/08884, mailed Aug., 27, 1999.
Shimizu, et al., “Chrondrocyte Migration to Type I collagen, Type II Collagen and Fibronectin”,Cell Struct. and Func., 20(6):584, 1995.
Official Action for U.S. Appl. No. 09/469,523, mailed Mar. 23, 2000.
Adami and Rice, “Metabolically Stabilized Peptide/DNA Formulations for Enhanced Gene Expression,”Pharm. Sci., 1998 AAPS Annual Meeting, vol. 1, S-286-S-287, 1998.
Choi et al., “Lactose-Poly(Ethylene Glycol)-Grafted Poly-L-Lysine as Hepatoma Cell-Targeted Gene Carrier,”Bioconjugate Chem., 9:708-718, 1998.
Midoux and Monsigny, “Efficient Gene Transfer by Histidylated Polylysine/pDNA Complexes,”Bioconjugate Chem., 10:406-411, 1999.
Adami et al., “Stability of Peptide-Condensed Plasmid DNA Formulations,”J. Pharm. Sci., 87(6):678-683, 1998.
Gottschalk et al., “A Novel DNA-Peptide Complex for Efficient Gene Transfer and Expression in Mammalian Cells,”Gene Therapy, 3:448,457, 1996.
Katayose and Kataoka, “Water-Soluble Polyion Complex Associates of DNA and Poly(Ethylene Glycol)-Poly (L-Lysine) Block Copolymer,”Bioconjugate Chem., 8:702-707, 1997.
Kwok et al., “Formulation of Highly Soluble Poly(Ethylene Glycol)-Peptide DNA Condensates,”J. Pharm. Sci., 88(10):996-1003, 1999.
Langer and Folkman, “Polymers for the Sustained Release of Proteins and Other Macromolecules,”Nature, 263:797-799, 1976.
Ledley, “Somatic Gene Therapy for Human Disease: Background and Prospects,”J. Pediatrics, 110:1-8, 1987.
Midoux et al., “Specific Gene Transfer Mediated by Lactosylated Poly-L-Lysine Into Hepatoma Cells,”Nucleic Acids Res., 21(4):871-878, 1993.
Nicolau et al., “In VivoExpression of Rat Insulin After Intravenous Administration of the Liposome-Entrapped Gene for Rat Insulin I,”Proc. Natl. Acad. Sci. USA, 80:1068-1072, 1983.
Smith et al., “Synthetic Peptide-Based DNA Complexes for Non-viral Gene Delivery,”Advanced Drug Delivery Reviews, 30:115-131, 1998.
Wadhwa et al., “Targeted Gene Delivery with a Low Molecular Weight Glycopeptide Carrier”Bioconjugate Chem., 6:283-291, 1995.
Wasan et al., “Plasmid DNA is Protected Against Ultrasonic Cavitation-Induced Damage when Complexed to Cationic Liposomes,”J. Pharm. Sci., 85(4):427-433, 1996.
Wolfert et al., “Characterization of Vectors for Gene Therapy Formed by Self-Assembly Of DNA with Synthetic Block Co-Polymers,”Human Gene Therapy, 7(10):2123-2133, 1996.
Rice Kevin Gerard
Wadhwa Manpreet S.
Marshall & Gerstein & Borun LLP
Priebe Scott D.
The Regents of the University of Michigan
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