Peptides encoded by nuclease sequences of actinomycetales and ap

Details Peptides encoded by nuclease sequences of actinomycetales and ap Peptides encoded by nuclease sequences of actinomycetales and ap

1995-06-06

1999-03-02

Marschel, Ardin H.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

5303871, A61K 3800, C07K 1600

Patent

active

058772731

ABSTRACT:
The present invention relates to nucleotide sequences of Actinomycetales, in particular of mycobacteria, to oligonucleotides contained within said nucleotide sequences, to their uses as primers for the synthesis of Actinomycetales DNA and as probes for the detection of DNA and/or the transcription products of Actinomycetales, in particular of mycobacteria, to the products of expression of said sequences, to their uses and to antibodies directed towards the said products, to a method for detecting and identifying Actinomycetales and its uses, as well as to immunogenic compositions comprising the said expression products.

REFERENCES:
patent: 4358535 (1982-11-01), Falkow et al.
Pao, C.C., et al., "The Detection of Mycobacterial DNA Sequences in Uncultured Clinical Specimens with Cloned Mycobacterium Tuberculosis DNA as Probes," Tubercle, 69(1):27-36 (Mar. 1988).
Picken, R.N., et al., "DNA Probes for Mycobacteria. I. Isolation of DNA Probes for the Identification of Mycobacterium Tuberculosis Complex and for Mycobacteria other than Tuberculosis (MOTT)," Molecular and Cellular Probes, 2:111-124 (1988).
Hance, A.J. et al., "Detection and Identification of Mycobacteria by Amplification of Mycobacterial DNA," Molecular Microbiology, 3(7):843-849 (1989).
Plikaytis, B.B. et al., "Rapid Sensitive and Specific Detection of Mycobacteria Using Gene Amplification Techniques," Abstracts of the Annual Meeting of the American Society for Microbiology, 89(0):162 (1989) Abstract No. U-43.

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