Peptides effective for diagnosis and detection of hepatitis C in

Details Peptides effective for diagnosis and detection of hepatitis C in Peptides effective for diagnosis and detection of hepatitis C in

1995-09-19

1998-04-07

Knode, Marian C.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

436820, 530350, G01N 33576, G07K 1418

Patent

active

057363218

ABSTRACT:
The present invention relates to novel linear and branched peptides specific for the diagnosis and prevention of hepatitis C virus (HCV) infection. More particularly, the present invention is directed to linear and branched synthetic peptides containing at least one antigenic site which is effective for detecting HCV-associated antibodies in patients using immunoassay techniques. In some cases, these peptides are also library peptides with degenerate amino acid positions. Preferred mixtures for detection of HCV antibodies are provided as well as a novel spliced peptide useful for blocking the non-specific reactivity of certain NS-3 conformational epitopes.

REFERENCES:
patent: 5582968 (1996-12-01), Wang et al.

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