Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Patent
1993-09-02
1996-01-02
Walsh, Stephen G.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
530326, 530806, 4241881, 42419611, 4242021, 435 71, 435975, C07K 14155, C07K 1700, A61K 3924, G01N 33536
Patent
active
054809665
ABSTRACT:
Peptides are derived from the envelope glycoprotein of HIV virus and having one of the following formulae ##STR1## in which X represents an NH.sub.2 group which is free or converted into an amide by one or two alkyl groups comprising from 1 to 5 carbon atoms, and Z represents either an OH group which is free or present as an alkoxy and thereby containing an alkyl group comprising from 1 to 5 carbon atoms, and in which at least one of the Cys residues is deleted, substituted or protected.
The peptides are applied to the detection of infection caused by the viruses HIV-1 and/or HIV-2 and to the vaccination against AIDS.
REFERENCES:
patent: 4499080 (1985-02-01), Duflot et al.
patent: 4629783 (1986-12-01), Cosand
patent: 4735896 (1988-04-01), Wang et al.
patent: 4768607 (1988-09-01), Molina
patent: 4812556 (1989-03-01), Vahlne et al.
patent: 4879212 (1989-11-01), Wang et al.
patent: 4957737 (1990-09-01), Heimer et al.
patent: 5128319 (1992-07-01), Arlinghaus
patent: 5260189 (1993-11-01), Formoso et al.
patent: 5283320 (1994-02-01), Vahlne et al.
patent: 5338829 (1994-08-01), Weiner et al.
Klasse et al., "Presence of antibodies to a putatively immunosuppressive part of human immunodeficiency virus (HIV) envelope glycoprotein gp41 is strongly associated with health among HIV-positive subjects" P.N.A.S. USA 85:5225-6229 (Jul. 1988).
Guyader, et al., "Genome organization and transactivation of the human immunodeficiency virus type 2.", Nature 326:662-669 (Apr. 1987).
Schulz et al, Principles of Protein Structure, pp. 14-16, Springer-Verlag (NY) 1979.
Robinson et al, "Antibodies to the Primary Immunodominant Domain of Human Immunodeficiency Virus Type 1 (HIV-1) Glycoprotein gp 41 . . . " J. Virol. 64(11):5301-5305 (Nov. 1990).
Hunt et al, "Discrimination Between HIV-1 and HIV-2 . . . " AIDS Res. Hum. Retrovir. 6(7):883-898 (Jul. 1990).
Goodman-Snitkoff et al, "Defining Minimal Requirements for Antibody Production . . . " Vaccine 8(3): 257-262 (Jun. 1990).
Schulz and Schirmer, Principles of Protein Structure, pp. 14-16, 1979.
Martin Jacques
Somme Gerard
Clonatec, S.A.
Walsh Stephen G.
LandOfFree
Peptides derived from the envelope glycoprotein of HIV viruses, does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Peptides derived from the envelope glycoprotein of HIV viruses, , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptides derived from the envelope glycoprotein of HIV viruses, will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-235972