Peptides derived from the C2 domain of epsilon PKC

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues

Reexamination Certificate

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C530S328000, C530S329000, C530S330000, C424S193100

Reexamination Certificate

active

07851587

ABSTRACT:
Peptides derived from the C2 regions of εPKC and methods of use, thereof, are described. These peptides modulate the activity of εPKC in an animal model of acute ischemic heart disease.

REFERENCES:
patent: 5478810 (1995-12-01), Stuber et al.
patent: 5776716 (1998-07-01), Ron et al.
patent: 5935803 (1999-08-01), Vasquez et al.
patent: 6683052 (2004-01-01), Thiam et al.
patent: 6933275 (2005-08-01), Mochly-Rosen et al.
patent: WO98/17299 (1998-04-01), None
patent: WO02/057413 (2002-07-01), None
patent: WO02/057413 (2002-07-01), None
patent: WO02/078600 (2002-10-01), None
patent: WO02/078600 (2002-10-01), None
patent: WO2005/025602 (2005-03-01), None
patent: WO2005/059124 (2005-06-01), None
patent: WO2005/059124 (2005-06-01), None
Theodore et al (J. Neurosci. 15: 7158-7167, 1995).
The International Search Report and Written Opinion for PCT Application No. PCT/US2007/021276, search report dated Jul. 22, 2008, 16 pages (2008).
Begley, R., Liron, T., Baryza, J., and Mochly-Rosen, D.,Biochem Biophys Res Commun.,318:949-54 (2004).
Chen, L., Hahn, H., Wu, G., Chen, C. H., Liron, T., Schechtman, D., Cavallaro, G., Banci, L., Guo, Y., Bolli, R., Dorn, G. W., 2nd, and Mochly-Rosen, D.,Proc Natl Acad Sci U S A, 98(20):11114-11119 (2001).
Dorn, G. W., 2nd, Souroujon, M. C., Liron, T., Chen, C. H., Gray, M. O., Zhou, H. Z., Csukai, M., Wu, G., Lorenz, J. N., and Mochly-Rosen, D.Proc Natl Acad Sci U S A96(22):12798-12803 (1999).
Gray, M. O., Karliner, J. S., and Mochly-Rosen, D.,J Biol Chem.,272(49):30945-30951 (1997).
Inagaki, K., Hahn, H. S., Dorn, G. W. and Mochly-Rosen, D.,Circulation, 108:869-875 (2003).
Johnson, J. A., Gray, M. O., Chen, C. H., and Mochly-Rosen, D.,J Biol Chem271(40):24962-24966 (1996).
Johnson, J.A., Gray, M.O., Karliner, J.S., Chen, C.H., and Mochly-Rosen, D.,Circ. Res., 79:1086-99 (1996).
Koponen, S., Kurkinen, K., Akerman, K. E., Mochly-Rosen, D., Chan, P. H., and Koistinaho, J.,J Neurochem.,86:442-450 (2003).
Ron, D., Luo, J., and Mochly-Rosen, D.,J Biol Chem., 270:24180-24187 (1995).
Saurin, A. T., Pennington, D. J., Raat, N. J., Latchman, D. S., Owen, M. J., and Marber, M. S.,Cardiovasc Res., 55:672-680 (2002).
Smith, B. L., and Mochly-Rosen, D.,Biochem Biophys Res Commun., 188(3):1235-1240 (1992).
Souroujon, M. C., and Mochly-Rosen, D.,Nat Biotechnol., 16:919-924 (1998).
Sweitzer, S. M., Wong, S. M., Peters, M. C., Mochly-Rosen, D., Yeomans, D. C., and Kendig, J. J.,J Pharmacol Exp Ther.,309(2):616-625 (2004).
Yedovitzky, M., Mochly-Rosen, D., Johnson, J. A., Gray, M. O., Ron, D., Abramovitch, E., Cerasi, E., and Nesher, R.,J Biol Chem.,272(3):1417-1420 (1997).
Zhang, Z. H., Johnson, J. A., Chen, L., El-Sherif, N., Mochly-Rosen, D., and Boutjdir, M.,Circ Res.,80:720-729 (1997).

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