Peptides comprising an immunogenic site of poliovirus and DNAs c

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 691, 4353201, 4352523, 43525233, 435255, 536 27, 935 65, C12N 1500, C12P 2100, C07H 1512

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050616234

ABSTRACT:
The invention relates to a DNA fragment containing at the most 315 pairs of nucleotides coding for a peptide which can be recognized by antibodies acting both against the "C" and "D" particles of the same poliovirus and against the VP-1 structural polypeptide of the capsid of this poliovirus. This peptide contains in particular the following sequence: Asp Asn Pro Ala Ser Thr Asn Lys Asp Lys Leu.

REFERENCES:
patent: 4694071 (1987-09-01), Almonds et al.
Racaniello, Proc. Natl. Acad. Sci., vol. 78, pp. 4887-4891, Aug. 1981.
Van der werf, Proc. Natl. Acad. Sci., vol. 80, pp. 5080-5089, Aug. 1983.
Nomoto, Proc. Natl. Acad. Sci., vol. 79, pp. 5743-5747, Oct. 1982.

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