Peptides based on the sequence of human lactoferrin and...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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Details

C514S011400, C514S012200, C514S013800, C530S300000, C530S317000, C530S324000, C530S326000, C530S327000, C424S009100

Reexamination Certificate

active

09743107

ABSTRACT:
The invention relates to new peptides formed of at least seven subsequent amino acids of the amino acids in position 12-40, counted from the N-terminal end, in the sequence constituting human lactoferrin, and preferably modifications thereof. The invention also relates to medicinal products comprising such peptides, especially intended for treatment and prevention of infections, inflammations and tumours. Furthermore, the invention relates to food stuff, e.g. infant formula food, comprising the above mentioned peptides.

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patent: 98/06425 (1998-02-01), None
Greene, T. and Wuts, P. , Protective Groups in Organic Synthesis, second ed., 1991, p. 293, published by John Wiley & Sons.
Daniel S. Chappel et al., “Structure-Function Relationship of Antibacterial Synthetic Peptides Homologous to a Helical Surface Region on Human Lactoferrin Against Escherichia coli Serotype 0111”, 1998, pp. 2434-2440.
Edward W. Odell et al., “Antibacterial Activity of Peptides Homologous to a Loop Region in Human Lactoferrin”, 1996, pp. 175-178.
International Search Report, Nov. 1999, 6 pp.
International Preliminary Examination Report, Nov. 2000, 11 pp., with copy of claims 1-52.
D.S. Chapple et al., “A Helical Region on Human Lactoferrin, Its Role in Antibacterial Pathogenesis”, Advances in Lactoferrin Research, 1998, vol. 443, p. 215-220.
W. Bellamy et al., “Identification of the Bactericidal Doman of Lactoferrin”, Biochimica et Biophysica Acta, 1121 (1992) 130-136.

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