Peptides and related molecules that modulate nerve growth...

Details Peptides and related molecules that modulate nerve growth... Peptides and related molecules that modulate nerve growth...

2005-07-19

2005-07-19

Russel, Jeffrey Edwin (Department: 1654)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Peptides containing saccharide radicals, e.g., bleomycins, etc.

C424S178100, C514S008100, C514S013800, C530S325000, C530S326000, C530S345000

Reexamination Certificate

active

06919426

ABSTRACT:
The present invention relates to certain biologically active peptides and polypeptides which can be used as therapeutics or prophylactics against diseases or disorders linked to NGF as the causative agent. In one aspect of the present invention, pharmacologically active polypeptides comprising peptides linked to one or more Fc domains are provided.

REFERENCES:
patent: 6660843 (2003-12-01), Feige et al.
patent: WO96/32478 (1996-10-01), None
patent: WO97/34631 (1997-09-01), None
patent: WO00/24782 (2000-05-01), None
Ramer, M.S., et al., Adrenergic Innervation of rat sensory ganglia following proximal or distal painful sciatic neuropathy: distinct mechanisms revealed by anti-NGF treatment. Eur J Neurosci 11:837-846 (1999).
Ro, L.S., et al., Effect of NGF and anti-NGF on neuropathic pain in rats following chronic constriction injury of the sciatic nerve. Pain 79: 265-274 (1999).

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