Peptides and nucleic acids derived from Eisenia foetida...

Details Peptides and nucleic acids derived from Eisenia foetida... Peptides and nucleic acids derived from Eisenia foetida...

2006-06-13

2006-06-13

Minnifield, Nita (Department: 1645)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

C530S300000, C424S093100, C424S520000, C424S537000, C435S069100

Reexamination Certificate

active

07060790

ABSTRACT:
The invention concernsEisenia foetidapolypeptides and peptides, particularly recombinant polypeptides, which are useful in tumour therapy, microbial infection, inflammation or immunology. The invention also relates to a process for preparing the above-mentioned polypeptides and peptides. Furthermore the invention concerns nucleic acids coding for said polypeptides and peptides.

REFERENCES:
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patent: WO 99/31229 (1999-06-01), None
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Bilej et al, European Cytokine Network, Mar.-Apr. 1994.
Bilej et al, Immunology Letters, 45, 1995.
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Bilej at al (Immunology Letters, 45, 1995).
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Beschin et al., “Identification and Cloning of a Glucan- and Lipopolysaccharide-binding Protein fromEisenia foetidaEarthworm Involved in the Activation of Prophenoloxidase Cascade”,The Journal of Biological Chemistry,vol. 273, No. 38, pp. 24948-24954, Sep. 18, 1998.
Bilej et al., “Identification of a cytolytic protein in the coelomic fluid ofEisenia foetidaearthworms”,Immunology Letters,vol. 45, No. 1-2, pp. 123-128, Feb. 1995.
Bilej et al., “Identification of TNF-Like Activity in Earthworms”,European Cytokine Network,vol. 5, No. 2, p. 99, 1994.
Lassegues et al., “Sequence and expression of anEisenia-fetida-derived cDNA clone that encodes the 40-kDa fetidin antibacterial protein”,Eur. J. Biochem.,vol. 246, No. 3, pp. 756-762, Jun. 15, 1997.
Lucas et al., “Mapping the Lectin-Like Activity of Tumor Necrosis Factor”,Science,vol. 263, pp. 814-817, Feb. 11, 1994.
PCT International Search Report, PCT/EP98/08169, dated Jul. 6, 1999, 7 pages, listing the above-identified documents.
PCT International Perliminary Examination Report, PCT/EP98/08169, dated Mar. 17, 2000, 8 pages.

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