Peptides and medical use thereof

Details Peptides and medical use thereof Peptides and medical use thereof

1988-07-21

1991-03-05

Springer, David B.

Drug, bio-affecting and body treating compositions

Identification or warning feature

Taste or smell or chemical irritation to the eye, nose, or...

514 15, 530328, 530327, C07C10352, A61K 3700

Patent

active

049976486

ABSTRACT:
Of therapeutic value in various contexts in which the cyclosporins are used, for example as anti-bacterial agents and particularly as immunosuppressive and anti-inflammatory agents, are acyclic undecapeptides having the formula (I)

REFERENCES:
patent: 4075194 (1978-02-01), Sela et al.
patent: 4108985 (1978-08-01), Ruegger et al.
patent: 4117118 (1978-09-01), Harri et al.
patent: 4594244 (1986-06-01), Lehner et al.
McDermott Jr. et al., "N-Methylamino Acids in Peptide Synthesis . . . ", Canadian Journal of Chemistry 56:2562-2570, 1973.
Galpin IJ, et al., "Synthesis of Linear Undecapeptide . . . ", Tetrahedron 44(6):1773-1782, 1988.
Galpin IJ, "Synthesis of Two Linear Fragments . . . ", Tetrahedron 44(6):1763-1772, 1988.

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