Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2011-03-01
2011-03-01
Gussow, Anne M. (Department: 1643)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C424S130100, C424S133100, C424S134100, C424S138100, C435S007200, C435S007230
Reexamination Certificate
active
07897351
ABSTRACT:
The invention relates to methods of inhibiting proliferation or growth of tumor cells and/or inducing cell death in cancer cells. This invention relates to the use of antibodies, hybridomas and pharmaceutical compositions containing same, for inhibiting growth or proliferation and inducing death in epithelial, colon, lung, breast and ovarian tumor cells or other cells which express MUC1 proteins.
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patent: WO 02/22685 (2002-03-01), None
Rosenblum, Shawver, Marks, Brink, Cheung, and Langton-Webster. Recombinant immunotoxins directed against the c-erb-2/HER2
eu oncogene product: in vitro cytotoxicity, pharmacokinetics, and in vivi efficacy studies in xenograft models. Clinical Cancer Research, 1999. vol. 5, pp. 865-874.
Hartman et al.,International Journal of Cancer, 82:256-267 (Jun. 3, 1999).
Zrihan-Licht et al.,European Journal of Biochemistry, 224 :787-795 (1994).
Price et al.,Tumor Biology, 19(Suppl. I):1-20 (1998).
Hilkens and Boer,Tumor Biology, 19(Suppl. I):67-70 (1998).
Smorodinsky Nechaama Ina
Wreschner Daniel H.
Yoeli-Lerner Merav
Browdy and Neimark PLLC
Gussow Anne M.
Ramot at Tel-Aviv University Ltd.
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