Peptides affecting gonadal function

Details Peptides affecting gonadal function Peptides affecting gonadal function

1982-03-01

1983-05-10

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Reduced antigenicity, reduced ability to bind complement, or...

2601125LH, A61K 3700, C07C10352

Patent

active

043829228

ABSTRACT:
LRF analogs having a modified D-Phe residue in the 6-position act as superagonists exhibiting potencies many times more than that of LRF. The peptides or their nontoxic salts can be administered by intravenous, subcutaneous, sublingual, oral, intravaginal, intranasal or rectal routes. The peptides can be used to regulate fertility in male and female mammals, including human beings.
The peptides are represented by the following formula:

REFERENCES:
patent: 4234571 (1980-11-01), Nestor et al.

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