Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – In an organic compound
Patent
1995-07-12
1997-07-22
Kight, John
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
In an organic compound
530328, 530327, 530300, 534 10, 534 14, A61K 5100, A61M 3614
Patent
active
056501340
ABSTRACT:
Somatostatin peptides bearing a chelating group selected from a bifunctional N.sub.4 -chelating group particularly suitable for Tc, Rh, Cu, Co or Re-labelling, and a bifunctional polyamino-polycarboxylic acid chelating group are complexed with a .alpha.-, .beta.-, .gamma.- or positron-emitting nuclide or a nuclide with Auger-e.sup.- -cascades and are useful as radiopharmaceuticals.
REFERENCES:
patent: 4678667 (1987-07-01), Meares et al.
patent: 4849207 (1989-07-01), Sakata et al.
patent: 5006643 (1991-04-01), Fazio et al.
patent: 5057302 (1991-10-01), Johnson et al.
patent: 5112953 (1992-05-01), Gustavson et al.
patent: 5219555 (1993-06-01), Bremer et al.
patent: 5428154 (1995-06-01), Gansow et al.
Kline et al (1991). Bioconjugate Chemistry, vol. 2, pp. 26-31. Carboxymethyl-Substituted Bifunctional Chelators: Preparation of Aryl Isothiocyanate Derivatives of 3-(carboxymethyl) 3-a zapentanedioic acid, 3,12-bis(carboxymethyl)-6,9-dioxa-3,12-diazatetradecanedioic Acid, and 1,4,7,10-Tetraazacyclodedecane-N,N',N",N'"-tetraacetic Acid for Us a Protein Labels.
Lewis et al (1994) Bioconjugate Chemistry, vol. 5, No. 6 pp. 565-576. A Facile, Water Soluble Method for Modification of Proteins with DOTA.
Holum (1991) Elements of General, Organic, and Biological Chemistry pp. 42-47.
Improved in Vivo Stability and Tumor Targeting of Bismuth-labeled Antibody Cancer Research 50, 4221-4226, Jul. 15, 1990.
J. Org. Chem., vol. 58, No. 24, 1993 pp. 6895-6899.
Chemical Abstracts--vol. 118, 1993; 255354r.
Radiolabeled Octreotide--S. J. Mather, et al. Cell Biophysics--vol. 21, 1992--pp. 93-107.
Albert Rainer
Macke Helmut
Honor Robert S.
Jones Dameron L.
Kassenoff Melvyn M.
Kight John
McGovern Thomas O.
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