Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...
Patent
1994-04-20
1997-02-11
Mosher, Mary E.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Amino acid sequence disclosed in whole or in part; or...
4241931, 4242391, 514 13, 530326, 930200, A61K 3908, A61K 3810, C12N 708
Patent
active
056018266
ABSTRACT:
The invention provides an immunogen against tetanus toxin including a peptide having a single, linear, antigenic, tetanus-toxin-specific epitope. The epitope is derived from the heavy chain C fragment of the toxin. In a preferred embodiment, the immunogen includes the last 20 amino acids of the toxin, including the carboxy terminus. Antibodies, including antipeptide antibodies, are also provided as well as methods of vaccination.
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Mosher Mary E.
The United States of America as represented by the Department of
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