Peptide which inhibits gonadal function

Details Peptide which inhibits gonadal function Peptide which inhibits gonadal function

1978-06-26

1980-08-19

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Reduced antigenicity, reduced ability to bind complement, or...

2601125LH, A61K 3700, C07C10352

Patent

active

042184398

ABSTRACT:
A method for preventing reproduction by administering to male mammals a peptide which inhibits the secretion of gonadotropins by the pituitary gland and inhibits the release of steroids by the gonads. The peptide has the structure:

REFERENCES:
patent: 3836640 (1974-09-01), Laurence
patent: 4034082 (1977-07-01), Johnson et al.
patent: 4081533 (1978-03-01), Cheesman
Sandow, et al., Acta Endocr. 84, Suppl. 208, p. 33 (1977).
Auclair, et al., BBRC 76 855-862 (1977).
Auclair, et al., Endocunology 101, 1890-1893 1977.
Pelletier, et al., Endocrinology 103, No. 2, pp. 641-643 1978.
Jaramillo, et al., Int. J. Fertil. 22 77 (1977).
Turner, et al., Fertility and Sterility 27, No. 5, p. 545 (1976).
Cory, et al., Biochem. and Biophys. Res. Comn. 67, 1975, pp. 576-582.

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