Peptide vaccine for inducing the production of anti-amyloid...

Details Peptide vaccine for inducing the production of anti-amyloid... Peptide vaccine for inducing the production of anti-amyloid...

2007-02-16

2011-10-11

Kemmerer, Elizabeth C (Department: 1649)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Conjugate or complex

C424S185100, C424S190100, C424S245100, C424S247100, C424S248100, C536S023400

Reexamination Certificate

active

08034353

ABSTRACT:
An object of the present invention is to provide a peptide vaccine for preventing and/or treating diseases caused by amyloid β-peptide, such as Alzheimer's disease. The present invention solves the above object by providing a peptide vaccine constructed by inserting a peptide having an amino acid sequence of a cell attachment motif of a cell adhesive molecule to a peptide which consists of a peptide having an amino acid sequence of multiagretope type T-cell epitope, which has been generated immunological memory, or a peptide including the same; an linker peptide; and a peptide having an amino acid sequence of a B cell epitope which is a specific region of amyloid β-peptide or a peptide including the same.

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