Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector
Reexamination Certificate
2007-08-28
2007-08-28
Campell, Bruce R. (Department: 1648)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
C424S192100
Reexamination Certificate
active
10258480
ABSTRACT:
This invention is concerned with a peptide tag having sequence SSTSSDFRDR or GVSSTSSDFRDR derived from transactivator protein E2 of Bovine Papillomavirus type 1, and the fusion polypeptide containing said peptide tag, and the expression vector comprising the oligonucleotide sequence encoding said peptide tag. The invention relates also to the antibodies specific for the peptide tag and the methods for detecting and purifying tagged proteins.
REFERENCES:
patent: 5674835 (1997-10-01), Androphy et al.
patent: 5679543 (1997-10-01), Lawlis
patent: 5989868 (1999-11-01), Harrison et al.
Kurg et al. Journal of Virology. Jun. 1999; 73 (6): 4670-4677.
Sheibani. Preparative biochemistry and biotechnology. 1999; 29 (1): 77-90, abstract only.
Kaldalu et al., “Monitoring and Purification of Proteins Using Bovine Papillomavirus E2 Epitope Tags”,BioTechniques, vol. 28, No. 3, Mar. 2000, pp. 456-462, XP-002187757.
Giri et al., “Structural and Mutational Analysis of E2 Trans-Activating Proteins of Papillomaviruses Reveals Three Distinct Functional Domains,”The EMBO Journal, vol. 7. No. 9, pp. 2823-2929, 1988.
Iives et al., “Long-Term Episomal Maintenance of Bovine Papillomavirus Type 1 Plasmids Is Determined by Attachment to Host Chromosomes, Which Is Mediated by the Viral E2 Protein and Its Binding Sites,”Journal of Virology, vol. 72, No. 5, pp. 4404-4412, 1999.
Jarvik et al., “Epitope Tagging,”Annu. Rev. Genet, vol. 32, pp. 601-618, 1998.
Juronen et al., “FPLC Purification of Mouse Monoclonal Antibodies from Ascitic Fluid Using Blue DEAE and Thiophilic Sorbents,”Journal of Immunological Methods, vol. 136, pp. 103-109, 1991.
Kaldalu et al., “TOL Plasmid Transcription Factor XyIS Binds Specifically to thePMOperator Sequences,”Molecular Microbiology, vol. 20, No. 3, pp. 569-579, 1996.
Kaldalu et al., “Functional Domains of the TOL Plasmid Transcription Factor XyIS,”Journal of Bacteriology, vol. 182, No. 4, pp. 1118-1126, 2000.
Koljak et al., “The Basis of Prostaglandin Synthesis in Coral,”The Journal of Biological Chemistry, vol. 276, No. 10, pp. 7033-7040, 2001.
Kurg et al., “Effect of Bovine Papillomavirus E2 Protein-Specific Monoclonal Antibodies on Papillomavirus DNA Replication,”Journal of Virology, vol. 73, No. 6, pp. 4670-4677, 1999.
Langel et al., “Design of Chimeric Peptide Ligands to Galanin Receptors and Substance P Receptors,”Int. J. Peptide Protein Res., vol. 39, pp. 516-522, 1992.
Lepik et al., “p53 Protein Is a Suppressor of Papillomavirus DNA Amplificational Replication,”Journal of Virology, vol. 72, NO. 8, pp. 6822-6831, 1998.
Piirsoo et al., “CisandTransRequirements for Stable Episomal Maintenance of the BPV-1 Replicator,”The EMBO Journal, vol. 15, No. 1, pp. 1-11, 1996.
Sedman et al., “Binding of the E1 and E2 Proteins to the Origin of Replication of Bovine Papillomavirus,”Journal of Virology, vol. 71, No. 4, pp. 2887-2896, 1997.
Spalholtz et al., “Transactivation of a Bovine Papilloma Virus Transcriptional Regulatory Element by the E2 Gene Product,”Cell, vol. 42, pp. 183-191, 1985.
Tanaka et al., “Differential Transcriptional Activation by Oct. 1 and Oct. 2: Interdependent Activation Domains Induce Oct. 2 Phosphorylation,”Cell, vol. 60, pp. 375-386, 1990.
Trifan et al., “Overexpression of Cycloosygenase-2 Induces Cell Cycle Arrest,”J. Biol. Chem, vol. 274, Issue 48, pp. 34141-34147, 1999.
Ustav et al., “Transient Replication of BPV-1 Requires Two Viral Polypeptides Encoded by the E1 and E2 Open Reading Frames,”The EMBO Journal, vol. 10, No. 2, pp. 449-457, 1991.
Kaldalu Niilo
Kurg Reet
Ustav Mart
Campell Bruce R.
Dodds John
Dodds and Associates
Kinsey Nicole E
Quattromed Ltd.
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