Peptide substrates of a proteolytic ADAM33 polypeptide and...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase

Reexamination Certificate

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C530S327000, C530S328000, C530S345000

Reexamination Certificate

active

07067273

ABSTRACT:
The present invention discloses peptide substrates of a proteolytic ADAM33 polypeptide. The present invention also discloses methods of identifying additional substrates of a proteolytic ADAM33 polypeptide. Furthermore, the present invention discloses methods of identifying compounds that inhibit the proteolytic activity of a proteolytic ADAM33 polypeptide.

REFERENCES:
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Yoshinaka et al., “Identification and characterization of novel mouse and human ADAM33s with potential metalloprotease activity,”Gene, 282(1-2):227-236 (2002).

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