Peptide-substituted heterocyclic immunostimulants

Details Peptide-substituted heterocyclic immunostimulants Peptide-substituted heterocyclic immunostimulants

1984-10-19

1986-10-28

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 18, 514 19, 530330, 530331, 530332, A61K 3702, C07K 702, C07K 506, C07K 508, C07K 510

Patent

active

046199152

ABSTRACT:
Peptide-substituted heterocyclic compounds having the formula below, pharmaceutically acceptable salts thereof and intermediates therefor; processes for their preparation and use as immunostimulant and antiinfective agents. ##STR1## wherein R is a 5- or 6-membered N-containing heterocyclyl moiety which can have an additional hetero atom selected from N, S or O; R.sup.1 is hydrogen or (C.sub.1-4)alkyl; x is 0 or an integer from 1 to 5; and y is 0 or 1; provided that when y is 0, said N-containing heterocyclyl moiety is linked to the ##STR2## group at its N atom.

REFERENCES:
patent: 4322341 (1982-03-01), Kitaura et al.
patent: 4427581 (1984-01-01), Miyazaki et al.
Kitaura et al., J. Med. Chem., 25, 335-337 (1982).

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