Peptide reagent for the detection of human cytomegalovirus...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...

Reexamination Certificate

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Details

C424S184100, C424S185100, C424S204100, C424S230100, C435S004000, C435S005000, C435S007100, C530S300000, C530S350000

Reexamination Certificate

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06936251

ABSTRACT:
The invention relates to a peptide reagent comprising peptides immunochemically reactive with antibodies to the human cytomegalovirus (CMV). New antibodies directed to said peptides or fragments thereof are also part of the invention. Also cell lines capable of producing monoclonal antibodies are part of the invention. The invention also relates to a method for the detection of CMV or antibodies directed against CMV in a test fluid and a test kit to be used when applying the said detection methods. Detection of CMV in a test fluid or tissue specimen using antibodies, monoclonal and polyclonal, directed to said peptide, which have the characteristics of detecting both native and denatured DMV proteins are also part of said invention.

REFERENCES:
patent: 5744298 (1998-04-01), Stuber et al.
patent: 5859185 (1999-01-01), Stuber et al.
patent: 6120989 (2000-09-01), Vornhagen et al.
patent: 3619902 (1988-03-01), None
patent: 4128684 (1993-04-01), None
patent: 4426453 (1995-11-01), None
patent: 236145 (1987-09-01), None
patent: 0 248 909 (1987-12-01), None
patent: 0 330 051 (1989-08-01), None
patent: WO 92/00323 (1992-01-01), None
Ayata et al., Journal of General Virology, vol. 43, pp. 380-392 (1994).
NCBI printout of Accession P06473, Glycoprotein B precursor (Jan 1988).
NCBI printout of Accession P13200, 28 KD Structural Phosphoprotein (Jan 1990).
Sundqvist et al., Journal of Clinical Microbiology, vol. 30, No. 10, pp. 2735-2739 (Oct 1992).
NCBI printout of Accession P08318, Large Structural Phosphoprotein (PP150) . . . (Aug 1988).
Ripalti et al., Journal of Clinical Microbiology, vol. 32, No. 2, pp. 358-363 (Feb 1994).
Landini et al., Journal of Clinical Microbiology, vol. 29, No. 9, pp. 1863-1872 (Sept 1991).
Giugni et al. 1992.Journal of Virology73:2367-2374.
Marshall et al. 1994.Journal of Medical Virology43:77-83.
Meyer et al. Sep. 1989. Database PIR 68, Accession No. WMBE28.
Shiu et al. Feb. 1995. Database PIR 68, Accession No. S40226.
Ayata et al. “Different Antibody Response to a Neutralizing Epitope of Human Cytomegalovirus Glycoprotein B Among Seropositive Individuals”Journal of Medical Virology43:386-392 (1994).
Greijer et al. “Molecular Fine-Specificity Analysis of Antibody Responses to Human Cytomegalovirus and Design of Novel Synthetic-Peptide-Based Serodiagnostic Assays”Journal of Clinical Microbiology37(1):179-188 (1999).
International Search Report corresponding to PCT/EP 97/03717 mailed on Nov. 14, 1997.
Van Zanten et al. “Comparative Immunoblot Analysis with Ten Different, Partially Overlapping Recombinant Fusion Proteins Derived From Five Different Cytomegalovirus Proteins”Microbiologica18:223-228 (1995).

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