Peptide purification method using novel linker and solid-phase l

Organic compounds -- part of the class 532-570 series – Organic compounds – Sulfur containing

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

568 27, 568 28, 568 29, 568 31, 568 37, 562557, 530333, 530335, 530337, 530344, C07C31704

Patent

active

059945885

ABSTRACT:
Disclosed are novel compounds which are used as linkers to bind peptides to solid support. The novel compounds can be used for the purification of synthesized peptides and are represented by the following structural formula:

REFERENCES:
patent: 4304715 (1981-12-01), Hudson et al.
patent: 4341865 (1982-07-01), Voss
patent: 4426481 (1984-01-01), Sullivan
patent: 5151443 (1992-09-01), Henrick
patent: 5155271 (1992-10-01), Aeschlimann
patent: 5256549 (1993-10-01), Urdea
patent: 5391711 (1995-02-01), Funakoshi
Tesser, Int J Pept Prot Res 7, 295, 1975.
Diaz, Bioorganic Chem 8, 429-442, 1979.
Funakoshi Proc Natl Acad Sci 88, 6981, '91.
Canne, Tetrahedron Letters 38, 3361, 1997.
Krieger, D. E., et al., "Affinity Purification of Synthetic Peptides," Proc. Natl. Acad. Aci. USA., 73:3160-3164 (1976).
Fujii, N., et al., "Studies on Peptides. CLV. Evaluation of Trimethylsilyl Bromide as a Hard-Acid Deprotecting Reagent in Peptide Synthesis," Chem. Pharm. Bull., 35:3880-3883 (1987).
Funakoshi, S., et al., "Chemoselective One-Step Purification Method for Peptides Synthesized by the Solid-Phase Technique," Proc. Natl. Acad. Sci., 88:6981-6985 (1991).
Sucholeiki, I., and Lansbury, P. T., Jr., "Affinity Chromatographic Method for the Purification of Water-Insoluble Peptides," J. Org. Chem., 5478-5484.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Peptide purification method using novel linker and solid-phase l does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Peptide purification method using novel linker and solid-phase l, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptide purification method using novel linker and solid-phase l will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1674836

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.