Organic compounds -- part of the class 532-570 series – Organic compounds – Sulfur containing
Patent
1995-06-02
1999-11-30
Tsang, Cecilia J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Sulfur containing
568 27, 568 28, 568 29, 568 31, 568 37, 562557, 530333, 530335, 530337, 530344, C07C31704
Patent
active
059945885
ABSTRACT:
Disclosed are novel compounds which are used as linkers to bind peptides to solid support. The novel compounds can be used for the purification of synthesized peptides and are represented by the following structural formula:
REFERENCES:
patent: 4304715 (1981-12-01), Hudson et al.
patent: 4341865 (1982-07-01), Voss
patent: 4426481 (1984-01-01), Sullivan
patent: 5151443 (1992-09-01), Henrick
patent: 5155271 (1992-10-01), Aeschlimann
patent: 5256549 (1993-10-01), Urdea
patent: 5391711 (1995-02-01), Funakoshi
Tesser, Int J Pept Prot Res 7, 295, 1975.
Diaz, Bioorganic Chem 8, 429-442, 1979.
Funakoshi Proc Natl Acad Sci 88, 6981, '91.
Canne, Tetrahedron Letters 38, 3361, 1997.
Krieger, D. E., et al., "Affinity Purification of Synthetic Peptides," Proc. Natl. Acad. Aci. USA., 73:3160-3164 (1976).
Fujii, N., et al., "Studies on Peptides. CLV. Evaluation of Trimethylsilyl Bromide as a Hard-Acid Deprotecting Reagent in Peptide Synthesis," Chem. Pharm. Bull., 35:3880-3883 (1987).
Funakoshi, S., et al., "Chemoselective One-Step Purification Method for Peptides Synthesized by the Solid-Phase Technique," Proc. Natl. Acad. Sci., 88:6981-6985 (1991).
Sucholeiki, I., and Lansbury, P. T., Jr., "Affinity Chromatographic Method for the Purification of Water-Insoluble Peptides," J. Org. Chem., 5478-5484.
Fukuda Hiroyuki
Funakoshi Susumu
Funakoshi Setsuko
Lukton David
Tsang Cecilia J.
LandOfFree
Peptide purification method using novel linker and solid-phase l does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Peptide purification method using novel linker and solid-phase l, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptide purification method using novel linker and solid-phase l will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1674836