Peptide process for preparation thereof and use thereof

Details Peptide process for preparation thereof and use thereof Peptide process for preparation thereof and use thereof

1984-05-18

1989-07-18

Phillips, Delbert R.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Tripeptides, e.g., tripeptide thyroliberin , etc.

C07K 508, C07K 510, C07K 502

Patent

active

RE0329924

ABSTRACT:
The invention deals with novel peptides useful for the therapeutic treatment of infectious diseases caused by pathogenic microorganisms. Included is the peptide FR900156 having the structure: ##STR1## as well as the peptides of the structure ##STR2## wherein R.sup.1 is acyl;

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patent: 4130554 (1978-12-01), Holly et al.
patent: 4261976 (1981-04-01), Jolles
Dezelee; P., et al., Biochemistry, vol. 9, No. 4, pp. 823-831, 1970.
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Nakamura, T., et al., Agricultural and Biological Chemistry, vol. 41, pp. 763-768, 1977.
Abstracts of the Eleventh International Congress of Chemotherapy, Oct. 1-5, 1979, Abstracts 702.
Werner et al., Immunopotentiating Activities of a Microbial Tetrapeptide after Coupling with Lauric Acid, (a typed draft for presentation at the Eleventh Int. Cong. of Chemotherapy, Oct. 1-5, 1979).
Elloys, F., et al., Biochem. and Biophys. Res. Comm., vol. 59, pp. 1317-1325, 1974.
Kotani, S., et al., Abstracts of Societe de Chime Biologique International Symposium, Oct. 14-15, 1974, Paris.
Comptes Rendus Hebdomandaires des Seance de l'Academie des Sciences, Paris, 6260, pp. 1302-1304.
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Migliore-Samour, et al., Life Sciences, vol. 26, No. 11, pp. 883-888.
Kontani, C. A., vol. 83, 1975, item 161981z.

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