Peptide or its salts

Details Peptide or its salts Peptide or its salts

1994-05-09

1997-04-29

Tsang, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 16, 530326, 530328, A61K 3800, C07K 708, C07K 706

Patent

active

056249004

ABSTRACT:
Peptides having high binding activity for human interleukin-1 and represented by the following formula

REFERENCES:
Eastgate, et al. Lancet, pp. 706-709, 1988.
Pompidon et al, Lancet p. 1423.
Tanihara et al, vol. 188, No. 2, Biochem and Biophysical Research Comm. pp. 912-920, 1992.
Nature, vol. 343, N. 6256, pp. 341-346, Jan. 25, 1990, S.P. Eisenberg, et al., "Primary Structure and Functional Expression from Complementary DNA of a Human Interleukin-1 Receptor Antagonist".
Chemical Abstracts, vol. 111, No. 23, p. 463, Dec. 4, 1989, 111:213060s, A. Tagliabue, et al., "Defining Agonist Peptides of Human Interleukin-1.beta.".
Chemical Abstracts, vol. 109, No. 19, p. 143, Nov. 7, 1988, 109:164234z, S.H. Ferreira, et al., "Interleukin-1.beta. as a Potent Hyperalgesic Agent Antagonized by a Tripeptide Analog".
Chemical Abstracts, vol. 109, No. 21, p. 545, Nov. 21, 1988, 109:188459c, T. Musso, et al., "Effect of a Synthetic Nonapeptide of Human IL-1.beta. on the Cellular Immunoreactivity and In Vivo Growth of a Fibrosarcoma of BALB/c mice".
Chemical Abstracts, vol. 107, No. 21, p. 580, Nov. 23, 1987, 107:196195n, E.W. Palaszynski, "Synthetic C-Terminal Peptide of IL-1 Functions as a Binding Domain as well as an Antagonist for the IL-1 Receptor".

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