Peptide or its salt for autoimmune hyperthyroidism containing it

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence

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A61K 3800, C07K 500, C07K 700, C07K 1400

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active

054461294

ABSTRACT:
A peptide having the formula:

REFERENCES:
Russo et al., Chemcial Abstracts, vol. 116., p. 79, Abs No. 15935w.
Nagayama et al., Bioch., Biophys. Res. Comm., vol. 165, No. 3, pp. 1184-1190, 1989.
Morris II, et al., J. Clin Endocr. Metab., vol. 67 No. 4, pp. 707-712, 1988.
Biochemical And Biophysical Research Communications, vol. 178, No. 1, Jul. 15, 1991, pp. 165-172, T. Mori et al., "A Synthetic Oligopeptide Derived From Human Thyrotropin Receptor Sequence Binds To Graves' Immunoglobulin And Inhibits Thyroid Stimulating Antibody Activity But Lacks Interactions With TSH".
Biochemical And Biophysical Research Communications, vol. 165, No. 3, Dec. 29, 1989, pp. 1250-1255, F. Libert, et al., "Cloning, Sequencing And Expression Of The Human Thyroptropin (TSH) Receptor. Evidence For Binding Of Antibodies".

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