Peptide-metal chelate conjugates

Details Peptide-metal chelate conjugates Peptide-metal chelate conjugates

1998-03-13

1999-10-26

Dees, Jose' G.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

530329, 530317, 530311, 530300, 534 14, 424 111, 424 165, A61K 5100, A61M 3614

Patent

active

059723084

ABSTRACT:
This invention relates to diagnostic and radiodiagnostic agents, including radiolabeled scintigraphic imaging agents, and therapeutic and radiotherapeutic agents. The invention provides such agents and reagents for preparing such agents, and methods for producing and using such reagents. Specifically, the invention provides radiolabeled imaging agents and non-radioactively labeled imaging agents for imaging sites in a mammalian body and reagents for preparing these imaging agents. The invention also provides radiolabeled therapeutic agents, as well as non-radioactively labeled therapeutic agents, and reagents and methods for preparing these agents. The agents and reagents provided comprise a specific binding peptide, covalently linked to a metal ion-complexing moiety. Reagents, methods and kits for making such reagents, methods for labeling such reagents, and methods for using such labeled reagents are provided.

REFERENCES:
patent: 5225180 (1993-07-01), Dean et al.
patent: 5443815 (1995-08-01), Dean et al.
patent: 5556939 (1996-09-01), Flanagan et al.
patent: 5632969 (1997-05-01), Flanagan et al.
patent: 5783170 (1998-07-01), Dean

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