Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reissue Patent
2006-08-01
2006-08-01
McKelvey, Terry (Department: 1636)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S320100, C435S467000, C530S300000, C530S350000
Reissue Patent
active
RE039220
ABSTRACT:
delete-start id="DEL-S-00001" date="20060801" ?A methodology that allows for highly efficient transfer and stable integration of DNA into both established eukaryotic cell lines and primary cells, including non-dividing cells such as human peripheral blood monocytes and macrophages, entails the use of a synthetic polypeptide comprised of a peptide domain which corresponds to a nuclear localization signal sequence and a DNA binding domain which is rich in basic amino acids, separated by a hinge region of neutral acid which prevents stearic interference between the two domains.delete-end id="DEL-S-00001" ?insert-start id="INS-S-00001" date="20060801" ?A synthetic polypeptide that allows for highly efficient transfer of DNA into eukaryotic cells, including, for example, non-dividing cells such as human peripheral blood monocytes and macrophages.insert-end id="INS-S-00001" ?
REFERENCES:
patent: 4046722 (1977-09-01), Rowland
patent: 4671958 (1987-06-01), Rodwell et al.
patent: 4691006 (1987-09-01), Stevens
patent: 4847240 (1989-07-01), Ryser et al.
patent: 4867973 (1989-09-01), Goers et al.
patent: 4870023 (1989-09-01), Fraser et al.
patent: 4897355 (1990-01-01), Eppstein
patent: 4904582 (1990-02-01), Tullis et al.
patent: 4946778 (1990-08-01), Ladner et al.
patent: 4946787 (1990-08-01), Eppstein et al.
patent: 4950599 (1990-08-01), Bertling et al.
patent: 5024939 (1991-06-01), Gorman
patent: 5047227 (1991-09-01), Rodwell et al.
patent: 5071651 (1991-12-01), Sabara et al.
patent: 5084441 (1992-01-01), Shaw et al.
patent: 5108921 (1992-04-01), Low et al.
patent: 5135736 (1992-08-01), Anderson et al.
patent: 5156840 (1992-10-01), Goers et al.
patent: 5166320 (1992-11-01), Wu et al.
patent: 5169933 (1992-12-01), Anderson et al.
patent: 5171563 (1992-12-01), Abrams et al.
patent: 5182107 (1993-01-01), Friden
patent: 5196510 (1993-03-01), Rodwell et al.
patent: 5229490 (1993-07-01), Tam et al.
patent: 5283342 (1994-02-01), Gustavson et al.
patent: 5298422 (1994-03-01), Schwartz et al.
patent: 5326856 (1994-07-01), Coughlin et al.
patent: 5354844 (1994-10-01), Beug et al.
patent: 5420105 (1995-05-01), Gustavson et al.
patent: 5449761 (1995-09-01), Belinka, Jr. et al.
patent: 5482858 (1996-01-01), Huston et al.
patent: 5502037 (1996-03-01), Kondratyev
patent: 5503833 (1996-04-01), Redmond et al.
patent: 5514546 (1996-05-01), Kool et al.
patent: 5521290 (1996-05-01), Sivam et al.
patent: 5521291 (1996-05-01), Curiel et al.
patent: 5527885 (1996-06-01), Coughlin et al.
patent: 5541287 (1996-07-01), Yau et al.
patent: 5547932 (1996-08-01), Curiel et al.
patent: 5574142 (1996-11-01), Meyer, Jr. et al.
patent: 5576201 (1996-11-01), Mason et al.
patent: 5578287 (1996-11-01), Theodore et al.
patent: 5583020 (1996-12-01), Sullivan
patent: 5585468 (1996-12-01), Coughlin et al.
patent: 5589392 (1996-12-01), Short
patent: 5593866 (1997-01-01), Hancock et al.
patent: 5599704 (1997-02-01), Thompson et al.
patent: 5607691 (1997-03-01), Hale et al.
patent: 5608060 (1997-03-01), Axworthy et al.
patent: 5610052 (1997-03-01), Thompson et al.
patent: 5616490 (1997-04-01), Sullivan et al.
patent: 5622854 (1997-04-01), Draper
patent: 5630996 (1997-05-01), Reno et al.
patent: 5631236 (1997-05-01), Woo et al.
patent: 5631237 (1997-05-01), Dzau et al.
patent: 5635380 (1997-06-01), Naftilan et al.
patent: 5637471 (1997-06-01), Artavanis-Tsakonas et al.
patent: 5637481 (1997-06-01), Ledbetter et al.
patent: 5639275 (1997-06-01), Baetge et al.
patent: 5639655 (1997-06-01), Thompson et al.
patent: 5641662 (1997-06-01), Debs et al.
patent: 5648248 (1997-07-01), Zenke et al.
patent: 5652122 (1997-07-01), Frankel et al.
patent: 5654006 (1997-08-01), Fernandez et al.
patent: 5661025 (1997-08-01), Szoka, Jr. et al.
patent: 5668255 (1997-09-01), Murphy
patent: 5670483 (1997-09-01), Zhang et al.
patent: 5670617 (1997-09-01), Frankel et al.
patent: 5672479 (1997-09-01), Johnson et al.
patent: 5674703 (1997-10-01), Woo et al.
patent: 5674704 (1997-10-01), Goodwin et al.
patent: 5674835 (1997-10-01), Androphy et al.
patent: 5674977 (1997-10-01), Gariepy
patent: 5674980 (1997-10-01), Frankel et al.
patent: 5683874 (1997-11-01), Kool et al.
patent: 5686264 (1997-11-01), Gaynor et al.
patent: 5693531 (1997-12-01), Chiorini et al.
patent: 5714166 (1998-02-01), Tomalia et al.
patent: 5717058 (1998-02-01), Matthews et al.
patent: 5747641 (1998-05-01), Frankel et al.
patent: 5750367 (1998-05-01), Chan
patent: 5750390 (1998-05-01), Thompson et al.
patent: 5756264 (1998-05-01), Schwartz et al.
patent: 5756353 (1998-05-01), Debs et al.
patent: 5759517 (1998-06-01), Anderson et al.
patent: 5763209 (1998-06-01), Sukhatme
patent: 5770580 (1998-06-01), Ledley
patent: 5773227 (1998-06-01), Kuhn
patent: 5773583 (1998-06-01), Sukhatme
patent: 5780444 (1998-07-01), Kahne
patent: 5792751 (1998-08-01), Ledley
patent: 5795870 (1998-08-01), Kahne
patent: 5798209 (1998-08-01), Chan
patent: 5801158 (1998-09-01), Thompson et al.
patent: 5804604 (1998-09-01), Frankel et al.
patent: 5807746 (1998-09-01), Lin et al.
patent: 5808036 (1998-09-01), Kool et al.
patent: 5811297 (1998-09-01), Gopal
patent: 5821234 (1998-10-01), Dzau et al.
patent: 5827703 (1998-10-01), Debs et al.
patent: 5837533 (1998-11-01), Boutin
patent: 5840674 (1998-11-01), Yatvin et al.
patent: 5843643 (1998-12-01), Ratner
patent: 5844088 (1998-12-01), Hoffman et al.
patent: 5844089 (1998-12-01), Hoffman et al.
patent: 5844107 (1998-12-01), Hanson et al.
patent: 5847121 (1998-12-01), Yau
patent: 5851829 (1998-12-01), Marasco et al.
patent: 5858784 (1999-01-01), Debs et al.
patent: 5859226 (1999-01-01), Hunt et al.
patent: 5869337 (1999-02-01), Crabtree et al.
patent: 5872105 (1999-02-01), Kool et al.
patent: 5877302 (1999-03-01), Hanson et al.
patent: 5888762 (1999-03-01), Joliot et al.
patent: 5891683 (1999-04-01), Usman et al.
patent: 5908623 (1999-06-01), Baetge et al.
patent: 5914265 (1999-06-01), Roop et al.
patent: 5925564 (1999-07-01), Schwartz et al.
patent: 5945100 (1999-08-01), Fick
patent: 5955365 (1999-09-01), Szoka, Jr. et al.
patent: 5955647 (1999-09-01), Fitchen et al.
patent: 5958412 (1999-09-01), Welt et al.
patent: 5958764 (1999-09-01), Roop et al.
patent: 5962427 (1999-10-01), Goldstein et al.
patent: 5965371 (1999-10-01), Marasco et al.
patent: 5972699 (1999-10-01), Draper et al.
patent: 5972704 (1999-10-01), Draper et al.
patent: 5972900 (1999-10-01), Ferkol, Jr.
patent: 5977084 (1999-11-01), Szoka, Jr. et al.
patent: 5977307 (1999-11-01), Friden et al.
patent: 5981273 (1999-11-01), Curiel et al.
patent: 5989906 (1999-11-01), Thompson et al.
patent: 5990089 (1999-11-01), Szoka, Jr. et al.
patent: 5994109 (1999-11-01), Woo et al.
patent: 6004940 (1999-12-01), Marasco et al.
patent: 6008336 (1999-12-01), Hanson et al.
patent: 6010908 (2000-01-01), Gruenert et al.
patent: 6020202 (2000-02-01), Jessee
patent: 6022735 (2000-02-01), Curiel et al.
patent: 6022950 (2000-02-01), Murphy et al.
patent: 6022966 (2000-02-01), Gustavson et al.
patent: 6030822 (2000-02-01), Lechiner et al.
patent: 6033884 (2000-03-01), Woo et al.
patent: 6037329 (2000-03-01), Baird et al.
patent: 6037526 (2000-03-01), Grimsley et al.
patent: 6057298 (2000-05-01), Roop et al.
patent: 6066624 (2000-05-01), Woo et al.
patent: 6077663 (2000-06-01), Curiel et al.
patent: 6077835 (2000-06-01), Hanson et al.
patent: 6113946 (2000-09-01), Szoka, Jr. et al.
patent: 6117657 (2000-09-01), Usman et al.
patent: 6127114 (2000-10-01), Haseloff et al.
patent: 6130366 (2000-10-01), Herrera-Estrella et al.
patent: 6133024 (2000-10-01), Helene et al.
patent: 6136601 (2000-10-01), Meyer, Jr. et al.
patent: 6140466 (2000-10-01), Barbas, III et al.
patent: 6140491 (2000-10-01), Usman et al.
patent: 6143727 (2000-11-01), Roop et al.
patent: 6150168 (2000-11-01), Woo et al.
patent: 6171859 (2001-01-01), Herrnstadt et al.
patent: 6177554 (2001-01-01), Woo et al.
patent: 6184356 (2001-02-01), Anderson et al.
patent: 6190380 (2001-02-01), Abela
patent: 6200801 (2001-03-01), Ferkol, Jr. et al.
patent: 6217860 (2001-04-01), Woo et al.
patent: 6238914 (2001-05-01), Boyce
patent: 6242568 (2001-06-01), Barbas, III et al.
pate
Genetic Applications, LLC
McKelvey Terry
Patton & Boggs LLP
LandOfFree
Peptide-mediated gene transfer does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Peptide-mediated gene transfer, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptide-mediated gene transfer will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3609289