Peptide leukotriene receptor

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S387900, C424S143100

Reexamination Certificate

active

10932004

ABSTRACT:
A cDNA encoding a novel LTC4receptor has been isolated. Provision of the novel protein, an LTC4receptor, enabled binding experiments using the LTC4. By screening for compounds that modulate LTC4receptor activity based on these binding experiments, development of drugs targeting the LTC4receptor becomes possible.

REFERENCES:
patent: 5011912 (1991-04-01), Hopp et al.
patent: WO 01/36471 (2001-05-01), None
patent: WO 01/42269 (2001-06-01), None
patent: WO 01/59105 (2001-08-01), None
patent: WO 01/59118 (2001-08-01), None
patent: WO 01/94580 (2001-12-01), None
Harvey et al. Mouse Monoclonal Antibody to a Latent Epitope of Leucocyte Receptors for Leukotriene B4, May 1992, Immunology 76(1):122-128.
European Search Report dated Dec. 12, 2005, for EP-05-01-8471.
Koshino T. et al: “Effect of a Ca2+antagonist, nifedipine, on the experimental asthma mediated mainly by slow reacing substance of anaphylaxis.” Arzneimittel-Forshung, vol. 35, No. 8, 1985, pp. 1231-1236.
Yamamoto H. et al: “Inhibition of analgestic-induced asthma by leukotriene receptor antagonist ONO-1078”, American Journal of Respiratory and Critical Care Medicine, vol. 150, No. 1, Jul. 1994, pp. 254-257.
Cauvin C. et al: “Mechanisms of calcium antagonist-induced vasodilation.”, Annual Review of Pahrmacology and Toxicology, vol. 23, 1983, pp. 373-396.
Ooaki R. et al: “Therapeutic Effect of Pranlukast, a Selective Cysteinyl Leukotriene Receptor Antagonist, on Bronchial Asthma”, International Archives of Allergy and Immunology, vol. 114, No. 1, 1997, pp. 97-100.
Kreutner W. et al: “The effect of leukotrine antagonists, lipoxygenase inhibitors and selected standards on leukotriene allergic bronchospasm in guinea pigs”, Agents and Actions, vol. 28, No. 3-4, 1989, pp. 173-184.
Snyder D. W. et al: Leukotriene receptor antagonists as potential therapeutic agents., Annual Review of Pharmacology and Toxicology, vol. 29, 1989, pp. 123-143.
Jones T. R. et al: “L-649,923, Sodium Betta-S Gamma-R-4-3-4 Acetyl-3-Hydroxy-2-propylphenoxy Propylthio-Gamma-Hydroxy-Beta-Methylbenzenebutanoate, a selective, orally active leukotriene receptor antagonist”, Canadian Journal of Physiology and Pharmacology, vol. 64, No. 8, 1986, pp. 1068-1075.
J. Takasaki et al., Biochemical and Biophysical Research Communications 274, 316-322 (2000) “The Molecular Characterization and Tissue Distribution of the Human Cysteinyl Leukotriene CysLT2Receptor”.
C.E. Heise et al. The Journal of Biological Chemistry vol. 275, No. 39, Issue of Sep. 29, pp. 30536 (2000) “Characterization of the Human Cysteinyl Leukotriene 2 Receptor”.
Dahlen S.E., Leukotriene Receptors,Clin. Rev. Allergy Immunol., 17 (1-2): 179-191 (1999).
Yokomizo et al. A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis. Jun. 5, 1997, Nature 387:620-624.
Kaplan et al., Identification of a G Protein coupled Receptor Induced in Activated T Cells. Jul. 15, 1993, J. Immunol. 151-628-636.

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