Peptide leukotriene receptor

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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Details

C435S069100, C435S252300, C435S320100, C530S350000, C536S023500

Reexamination Certificate

active

06878525

ABSTRACT:
A cDNA encoding a novel LTC4receptor has been isolated. Provision of the novel protein, an LTC4receptor, enabled binding experiments using the LTC4. By screening for compounds that modulate LTC4receptor activity based on these binding experiments, development of drugs targeting the LTC4receptor becomes possible.

REFERENCES:
patent: WO 0136471 (2001-05-01), None
patent: WO 0142269 (2001-06-01), None
patent: WO 0159105 (2001-08-01), None
patent: WO 0159118 (2001-08-01), None
patent: WO 0194580 (2001-12-01), None
Kaplan et al. Identification of a G Protein Coupled Receptor Induced in Activated T Cells. Jul. 15, 1993, J. Immunol. 151:628 636.*
Yokomizo et al. A G-protein-coupled receptor for leukortriene B4 that mediates chemotaxis. Jun. 5, 1997, Nature 387:620-624.*
J. Takasaki et al., Biochemical and Biophysical Research Communications 274, 316-322 (2000) “The Molecular Characterization and Tissue Distribution of the Human Cysteinyl Leukotriene CysLT2Receptor”.
C. E. Heise et al., the Journal of Biological Chemistry vol. 275, No. 39, Issue of Sep. 29, pp. 30531-30536 (2000) “Characterization of the Human Cysteinyl Leukotriene 2 Receptor”.
Dahlen S.E., Leukotriene Receptors,Clin. Rev. Allergy Immunol.,17(1-2):179-191 (1999).

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