Peptide inhibitors of selectin binding

Details Peptide inhibitors of selectin binding Peptide inhibitors of selectin binding

1995-05-10

1997-02-11

Russel, Jeffrey E.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

11 to 14 amino acid residues in defined sequence

530328, 530329, 530330, A61K 3808, C07K 706

Patent

active

056022301

ABSTRACT:
The present invention provides novel peptides derived from portions of the sequence of amino acids 23-26 and 27-30 of P-selectin. The invention also provides pharmaceutical compositions comprising the peptides of the invention, and diagnostic and therapeutic methods utilizing the peptides and pharmaceutical compositions of the invention. The peptides of this invention can be used in the modulation or inhibition of coagulation processes or inflammatory processes.

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