Peptide inhibitors of mitogenesis and motogenesis

Details Peptide inhibitors of mitogenesis and motogenesis Peptide inhibitors of mitogenesis and motogenesis

1996-05-29

1999-06-15

Allen, Marianne P.

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

530326, 530324, 530300, C07K 700, A61K 3810

Patent

active

059121831

ABSTRACT:
The invention in the field of cell biology relates to novel peptides able to interact with intracellular signal transducers, thus interfering with signal transduction pathways leading to cell proliferation and motility.
The peptides of the invention may be chemically synthesized from single amino acids and/or preformed peptides of two or more amino acid residues.
The peptides of the invention find an useful application in the treatment of a neoplastic disease.

REFERENCES:
patent: 5559025 (1996-09-01), Ahorn et al.
patent: 5571509 (1996-11-01), Comoglio et al.
Rudinger, In "Peptide Hormones" (Jun. 1976) ed. J.A. Parsons. University Park Press, Baltimore, pp. 1-7.

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