Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1995-06-05
1998-12-15
Tsang, Cecilia J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530324, 530325, 530326, 530327, 530328, 530329, 530330, 514 15, 514 16, 514 17, A61K 3800, C07K 706, C07K 708, C07K 700
Patent
active
058497013
ABSTRACT:
Peptides derived from the second type 1 repeat of human endothelial cell thrombospondin which bind to the gelatin-binding domain of fibronectin have been isolated and synthetically produced. The peptides can be used to bind to fibronectin or other related collagen-binding proteins to inhibit fibronectin-dependent cell adhesion to collagen matrices and to inhibit interactions with collagen of other proteins that share homologies with the gelatin-binding domain of fibronectin.
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Guo Neng-hua
Krutzsch Henry C.
Negre Eric
Roberts David D.
Sipes John M.
Marshall S. G.
The United States of America as represented by the Department of
Tsang Cecilia J.
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