Peptide inhibitors against seprase

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase

Reexamination Certificate

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C514S016700

Reexamination Certificate

active

07374898

ABSTRACT:
The invention generally relates compositions and methods for the treatment of patients with melanoma and other malignant cancers. The compositions of the present invention are novel peptide sequences that inhibit seprase-mediated cell migration. Said sequences may also be used for diagnostics and library screening protocols.

REFERENCES:
patent: 2004/0053829 (2004-03-01), Pfizenmaier et al.
Kuks PFM et al. Xenopus laevis skin Arg-Xaa-Val-Arg-Gly-endoprotease, 1989, Journal of Biological Chemistry, v264, 14609-14612.

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