Peptide, immunogenic composition and vaccine or medical...

Details Peptide, immunogenic composition and vaccine or medical... Peptide, immunogenic composition and vaccine or medical...

2006-03-28

2006-03-28

Russel, Jeffrey Edwin (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C424S185100, C530S313000, C530S402000

Reissue Patent

active

RE039048

ABSTRACT:
The invention relates to a modified tandem LHRH-peptide vaccine preparation in which the amino acid glycine at position (6) of one or both LHRH decapeptides that constitute the tandem unit is substituted by a dextrorotatory amino acid that contains a side chain to which a carrier compound can be coupled. In addition, the tandem LHRH-peptide can be brought into a tandem-dimer form which is also suitable for producing a vaccine that is effective against LHRH (luteinizing hormone releasing hormone), also referred to as GaRH (gonadotropin-releasing hormone), for immunological castration to inhibit or affect reproductive functions or to affect behaviour in vertebrates in general and in domesticated animals and man in particular.

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