Peptide having immunopotentiating activity similar to thymosin a

Details Peptide having immunopotentiating activity similar to thymosin a Peptide having immunopotentiating activity similar to thymosin a

1985-06-10

1986-09-30

Moyer, Donald B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 21, 424 95, 530301, 530324, 530837, A61K 3724, A61K 3702, C07K 748

Patent

active

046147314

ABSTRACT:
A new biologically active polypeptide hormone has been isolated from calf thymosin fraction 5 and has been given the designation thymosin alpha.sub.11. The peptide contains seven additional amino acid residues at the carboxy terminus when compared to thymosin alpha.sub.1. Thymosin alpha.sub.11 is one of several peptides present in thymosin fraction 5 which participate in the regulation, differentiation and function of thymic dependent lymphocytes (T cells). The new peptide is approxomately 16 times as potent in the protection of subject animals against opportunistic infections as thymosin fraction 5 and approximately equal in potency to thymosin alpha.sub.1.

REFERENCES:
patent: 4079127 (1978-03-01), Goldstein et al.
patent: 4082737 (1978-04-01), McGregor et al.
patent: 4388234 (1983-06-01), Horecker
Goldstein, Allan L. "Thymic Hormones and Lymphokines", 1984, pp. 21-35, Plenum Press.

Affiliated with

Also associated with

Rating

Peptide having immunopotentiating activity similar to thymosin a does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Peptide having immunopotentiating activity similar to thymosin a, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptide having immunopotentiating activity similar to thymosin a will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-984885