Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2007-04-03
2007-04-03
Siew, Jeffrey (Department: 1642)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C436S064000, C436S500000
Reexamination Certificate
active
09856199
ABSTRACT:
The present invention provides a peptide fragment or a series of peptide fragments having a cell death-inhibitory activity, having the amino acid sequence consisting of 103 amino acid residues at the C-terminal of selenoprotein P, or having said amino acid sequence with one or several amino acid residues therein being deleted, substituted or added, or having a partial sequence of either of the above amino acid sequences, a medicament for treatment comprising said peptide fragment or a series of peptide fragments, an antibody to said peptide fragment or a series of peptide fragments, and a method for screening a cell death-inhibitory activity using said peptide fragment or a series of peptide fragments. The preferable peptide fragment or a series of peptide fragments of the present invention has the amino acid sequences shown in SEQ ID NO: 1 and/or SEQ ID NO: 2 or has a partial sequence thereof.
REFERENCES:
Rafferty et al (Biochem J May 15, 1998;332(Pt1):231-6).
Burgess et al., J of Cell Bio. 111:2129-2138, 1990.
Lazar et al. Molecular and Cellular Biology 8:1247-1252, 1988.
Bowie et al. Science, 247:1306-1310, 1990, p. 1306, col. 2.
Freshney (Culture of Animal Cells, A Manual of Basic Technique, Alan R. Liss, Inc., 1983, New York, p4).
Dermer (Bio/Technology, 1994, 12:320).
Craig B. Thompson, Science, vol. 267, Mar. 10, 1995, pp. 1456-1462.
Lixin Zheng et al., Nature, vol. 377, Sep. 28, 1995, pp. 348-351.
Takashi Suda et al., Cell, vol. 75, Dec. 17, 1993, pp. 1169-1178.
A. H. Wyllie, Nature, vol. 284, Apr. 10, 1980, pp. 555-556.
Lawrence H. Boise et al., Cell, vol. 74, Aug. 27, 1993, pp. 597-608.
Laura J.S. Greenlund et al., Neuron, vol. 14, Feb., 1995, pp. 303-315.
Paul A. Sandstrom et al., Proc. Natl. Acad. Sci. USA, vol. 90, May, 1993, pp. 4708-4712.
Yoshiro Kayanoki et al., J. Biochem., vol. 119, 1996, pp. 817-822.
Kristina E. Hill et al., Biomedical and Environmental Sciences, vol. 10, 1997, pp. 198-208.
G. Kohler et al., Nature, vol. 256, Aug. 7, 1975, pp. 495-497.
Sheryl M. Greenberg et al., Blood, vol. 72, No. 6, Dec., 1988, pp. 1968-1977.
Kristina E. Hill et al., Proc. Natl. Acad. Sci, USA, vol. 90, Jan., 1993, pp. 537-541.
D.E. Yelton et al., Curr Top Microbiol Immunol, vol. 81, pp. 1-7.
Katja Zurbonsen et al.; European Journal of Pharmacology, vol. 320, pp. 215-221, 1997.
Hill et al., Proc. Natl. Acad. Sci., vol. 90, No. 2, pp. 537-541 (1993).
Akesson et al., Biochim. Biophys. Acta, vol. 1204, No. 2, pp. 243-249 (1994).
Hill et al., J. Nutr., vol. 126, No. 1, pp. 138-145 (1996).
Persson-Moschos et al., Analyst, vol. 120, No. 3, pp. 833-836 (1995).
Arteel et al., Biol. Chem. vol. 379, Nos. 8-9 (Aug.-Sep. 1998).
Jun Yan et al.; The Journal of Neuroscience, vol. 18, No. 21, pp. 8682-8691 (Nov. 1, 1998).
Masaki Hirashima et al.; Biol. Pharm. Bull., vol. 26, No. 6, pp. 794-798 (2003).
Hirashima Masaki
Maeda Hiroaki
Nozaki Chikateru
Juridical Foundation The Chemo-Sero-Therapeutic Research Institu
Siew Jeffrey
Yaen C.
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