Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector
Reexamination Certificate
2003-03-27
2008-09-02
Helms, Larry R. (Department: 1642)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
C424S185100, C530S300000
Reexamination Certificate
active
07419669
ABSTRACT:
The invention relates to the production of peptide epitopes common to a plurality of antigens of the same multigene family, said epitopes containing at least one common pentapeptide sequence preceded by three amino acids at the N-terminal end and optionally followed by one or two amino acids at the C-terminal end. The invention also relates to polynucleotides coding for said epitopes. Said peptides and polynucleotides can be especially used in anti-tumour immunotherapy.
REFERENCES:
patent: 00 20581 (2000-04-01), None
patent: 00 52045 (2000-09-01), None
patent: 01 41787 (2001-06-01), None
patent: 01 42267 (2001-06-01), None
McIntyre et al, 1996, Cancer Immunol Immunother, 42: 246-250.
Tanzarella, Silvia et al. “Identification of a Promiscuous T-Cell Epitope Encoded by Multiple Members of the MAGE Family”, Cancer Research, vol. 59, No. 11, pp. 2668-2674, XP001132068, ISSN: 0008-5472 Jun. 1, 1999.
Graff-Dubois, Stephanie et al. “Generation of CTL Recognizing an HLA-A*0201-Restricted Epitope Shared by MAGE-A1,-A2,-A3,-A4,-A6,-A10, and -A12 Tumor Antigens: Implication in a Broad-Spectrum Tumor Immunotherapy”, Journal of Immunology. vol. 169, pp. 575-580, XP001109368 Jul. 1, 2002.
Graff-Dubois Stéphanie
Kosmatopoulos Kostas
Davis Minh-Tam
Helms Larry R.
Institut Gustave Roussy
Institut National de la Sante et de la Recherche Medicale
Oblon & Spivak, McClelland, Maier & Neustadt P.C.
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