Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1987-01-20
1990-03-20
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
548953, 548536, 548537, 548538, 546225, 546227, A61K 3764
Patent
active
049101900
ABSTRACT:
The invention concerns pharmaceutically useful trifluoromethyl ketone substituted di-, tri- and tetra-peptide derivatives of the formulae Ia, Ib, Ic set out hereinafter, and salts thereof, which are inhibitors of human leukocyte elastase. Also described herein are pharmaceutical compositions containing a peptide derivative and processes and intermediates for use in the manufacture of the peptide derivatives.
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Bergeson Scott H.
Edwards Philip D.
Schwartz John A.
Shaw Andrew
Stein Mark M.
ICI Americas Inc.
Jackson Thomas E.
Miano Rosemary M.
Phillips Delbert R.
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