Peptide derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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Details

C514S002600, C530S300000, C530S308000, C530S324000, C530S338000, C530S402000, C530S409000

Reexamination Certificate

active

07576059

ABSTRACT:
A pharmacologically active peptide hormone derivative in which the parent peptide hormone has been modified by introducing either a lipophilic substituent, W, in the N-terminal amino acid or a lipophilic substituent, Z, in the C-terminal amino acid of the parent peptide hormone or an analogue thereof, said lipophilic substituent having from 8 to 40 carbon atoms, has a protracted profile of action.

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patent: 6268383 (2001-07-01), Ellis
patent: 6458924 (2002-10-01), Knudsen et al.
patent: 0 511 600 (1992-11-01), None
patent: WO 93/15750 (1993-08-01), None
patent: WO 93/21320 (1993-10-01), None
patent: WO 95/03405 (1995-02-01), None
Muranishi et al., Trials of lipid modification of peptide hormones for intestinal discovery. J. Controlled Release 19, 179-188 (1992).
Abstract, File 73, Dialog Accession No. 8421240, Muranishi et al. (1992).
Abstract, File 434, Dialog Accession No. 12616071, Tenma et al. (1993).
Abstract, File 434, Dialog Accession No. 13565514, Yodoya et al. (1994).
Chemical Abstracts, vol. 123, No. 10, The Abstract No. 122862m, Cruz et al. (1995).
Chemical Abstracts, vol. 118, No. 16, The Abstract No. 154346j, Martins et al. (1993).

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