Peptide compounds of (L) amino acids and ring molecules, and the

Details Peptide compounds of (L) amino acids and ring molecules, and the Peptide compounds of (L) amino acids and ring molecules, and the

1995-12-15

1998-04-07

Weber, John P.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530331, 530800, A61K 3800, A61K 3806

Patent

active

057365180

ABSTRACT:
Compounds of general formula A--B--C in which: A is a monovalent radical of a L-ring molecule; B is a bivalent radical of a L-.alpha.-aminoacid; and C is a monovalent radical of a L-aromatic molecule. The compounds show an anti-hypertensive, analgesic, immuno-modulating and antiinflammatory activity, they are resistant to enzyme hydrolysis and they can be used for the preparation of drugs for oral administration.

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Haber et al. (1987) J. Cardiovas. Pharm., 10, 554-558.
Burger (1960) "Medicinal Chemistry", 2nd Ed. Interscience Publisheres, New York, pp. 565-581, 600-601.
Aldrich Catalog (1990-1991), pp. 112, 1064, 1234.

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