Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – In an organic compound
Reexamination Certificate
2002-03-01
2009-10-27
Jones, D L (Department: 1618)
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
In an organic compound
C514S010100, C530S317000, C424S001110, C424S001650, C534S014000
Reexamination Certificate
active
07608242
ABSTRACT:
A peptide-chelate conjugate with affinity for the ST receptor is disclosed, wherein the chelate is tetradentate. The peptide-chelate conjugate of the invention may be labelled with a radiometal to provide a metal complex. A radiopharmaceutical composition comprising the metal complex is provided. which is suitable for the diagnostic imaging of colorectal cancer. Also provided for in the invention is a kit for the preparation of the radiopharmaceutical preparation.
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Kwamena E. Baidoo, et.al. “Synthesis of A Diaminedithiol Bifunctional Chelating agent for Incorporation of Technetium-99M Into Biomolecules”, Bioconjugate Chemistry, American Chemical Society, Wash. US vol. 1, No. 2, 1990, pp. 132-137, XP000371813.
Bacon Edward R.
Cuthbertson Alan
Desai Vinay Chandrakant
Dixon Mark
Kasina Sudhakar
Bohlken Craig
GE Healthcare Limited
Jones D L
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