Peptide capable of binding to insulin-binding protein and...

Details Peptide capable of binding to insulin-binding protein and... Peptide capable of binding to insulin-binding protein and...

2011-03-15

2011-03-15

Audet, Maury (Department: 1654)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

15 to 23 amino acid residues in defined sequence

C514S001100, C424S001690

Reexamination Certificate

active

07906618

ABSTRACT:
The present invention relates to a peptide excellently capable of binding to a protein capable of binding to insulin (IBP), an adsorbent comprising the aforementioned peptide immobilized on a carrier, an adsorber comprising the aforementioned adsorbent, and a method of adsorbing IBPs by using the aforementioned adsorbent or adsorber.The peptide, adsorbent, adsorber and method provided by the present invention can selectively adsorb and remove IBPs efficiently, and therefore be used, for example, in the treatment of diseases, typically diabetes, in which such IBP acts as an aggravating factor.

REFERENCES:
patent: 5422339 (1995-06-01), Eisenbarth et al.
patent: WO-90/12814 (1990-11-01), None
patent: WO-00/33068 (2000-06-01), None
patent: WO-02/094344 (2002-11-01), None
International Preliminary Report on Patentability for PCT/JP2005/014596, dated Mar. 3, 2006, 7 pages.
Supplementary Partial European Search Report for counterpart EP Application No. 05770543.6, issued Sep. 20, 2007, 8 pages.
XP 002450105, Colon et al., Comparative peptidomics of the endocrine pancreas: islet hormones from the clawed frogXenopus laevisand the red-bellied newtCynops pyrrhogaster, Journal of Endocrinology, (2002), 175, pp. 769-777.

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