Peptide-based inhibitors of HIV replication

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 15, 514 16, 530327, 530328, 530329, A61K 3808, C07K 500

Patent

active

056461208

ABSTRACT:
Described herein are oligopeptides useful to inhibit replication in virally infected individuals. In a preferred embodiment of the invention, the oligopeptide is a D-arginine nonamer having N- and C-terminal protecting groups, which, at a 5 uM concentration, exhibits greater than 95% inhibition of HIV replication, in a standard assay.

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