Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 8 to 10 amino acid residues in defined sequence
Patent
1995-06-07
1998-08-04
Tsang, Cecilia J.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
8 to 10 amino acid residues in defined sequence
530327, 530329, 514 15, 514 16, 514 17, A61K 3808
Patent
active
057895317
ABSTRACT:
Described herein are oligopeptides useful to inhibit replication in virally infected individuals. In a preferred embodiment of the invention, the oligopeptide is a D-arginine nonamer having N- and C-terminal protecting groups, which, at a 3 uM concentration, exhibits greater than 95% inhibition of HIV replication, in a standard assay.
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Barnett Richard W.
Reid Lorne S.
Sonenberg Nahum
Sumner-Smith Martin
Allex Biopharmaceuticals, Inc.
Lukton David
Tsang Cecilia J.
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