Peptide-based compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S021100

Reexamination Certificate

active

07994134

ABSTRACT:
The invention relates to new peptide-based compounds for use as diagnostic imaging agents or as therapeutic agents wherein the agents comprise targeting vectors which bind to integrin receptors.

REFERENCES:
patent: 4647447 (1987-03-01), Gries et al.
patent: 5364613 (1994-11-01), Sieving et al.
patent: 5367080 (1994-11-01), Toner et al.
patent: 5846782 (1998-12-01), Wickham et al.
patent: 5888474 (1999-03-01), Dean et al.
patent: 5965107 (1999-10-01), Dean et al.
patent: 7351790 (2008-04-01), Cuthbertson et al.
patent: 7521419 (2009-04-01), Cuthbertson et al.
patent: 2003/0176639 (2003-09-01), Cuthbertson et al.
patent: 2003/0204049 (2003-10-01), Cuthbertson et al.
patent: 2008/0095715 (2008-04-01), Cuthbertson et al.
patent: 578083 (1994-01-01), None
patent: WO 89/00557 (1989-01-01), None
patent: WO 99.51638 (1990-10-01), None
patent: WO 90/14103 (1990-11-01), None
patent: WO 93/12819 (1993-07-01), None
patent: WO 95/14714 (1995-06-01), None
patent: WO 95/25543 (1995-09-01), None
patent: WO 95/26205 (1995-10-01), None
patent: WO 96/11023 (1996-04-01), None
patent: WO 97/06791 (1997-02-01), None
patent: WO 97/10507 (1997-03-01), None
patent: WO 97/25073 (1997-07-01), None
patent: WO 97/28830 (1997-08-01), None
patent: WO 98/10795 (1998-03-01), None
patent: WO 98/47541 (1998-10-01), None
patent: WO 98/54346 (1998-12-01), None
patent: WO 98/54347 (1998-12-01), None
patent: WO 99/39734 (1999-08-01), None
patent: WO 99/40214 (1999-08-01), None
patent: WO 01/77145 (2001-10-01), None
patent: WO 02/20610 (2002-03-01), None
patent: WO 02/26776 (2002-04-01), None
patent: WO2004/080492 (2004-09-01), None
Ruoslahti, J. Clin. Invest., 87: 1-5 (1991).
Conforti, G., et al. (1992) Blood 80: 37-446.
Pasqualini, R., et al. (1997) Nature Biotechnology 15: 542-546.
Bauer, J.S., (1992) J. Cell Biol. 116: 477-487.
Gehlsen, K.R., (1988) J. Cell biol. 106: 925-930.
Haubner et al. In the J. Nucl. Med. (1999).
Merrifield: J. Am. Chem. Soc., 85: 2149 (1964).
International Preliminary Examination Report dated Jan. 9, 2004 for PCT/NO02/00250.
Hallahan, D. “Targeting drug delivery to radiation-induced neoantigens in tumor microvasculature” Journal of Controlled Release 74 (2001) pp. 183-191.
Harris, T. “Tc-99m-labeled fibrinogen receptor antagonists: design and synthesis of cyclic RGD peptides for the detection of thrombi” Bioorganic & Medicinal Chemistry Letters vol., 6, No. 15, pp. 1741-1746.
Liu, et.al. “99mTc-labeling of a hydrazinonicotinamide-conjugated vitronectin receptor antagonists useful for imaging tumors ”bioconjugate Chem. 2001, 12, pp. 623-629.
Merrifield “Solid phase peptide synthesis” Contribution for the Rockfeller Institute, published Jan. 31, 1963, pp. 2149-2154.
Pearson, et.al. Thrombus imaging using technetium-99-m-labeled high potency GP IIb/IIIa receptor antagonists. J. Med. Chem 1996, 39, pp. 1372-1382.
Rajopadhye, et.al. synthesis and technetium-99m labelling of cyclic GP IIB/lia receptor antagonist conjugated to 4, 5-bis(mercaptoacetamido)-Pentanoic Acid (MAPT): Biorganic & Medicinal Chemistry Letters, 1996, vol. 6, No. 15, pp. 1737-1740.
Rajopadhye, et.al. “Synthesis evaluation and Tc-99m complexation of a hydrazinonicotinyl conjugate of hydrazinonicotinyl conjugate of a GPII/lia antagonist cyclic peptide for the detection of deep vein thrombosis” Bioorganic & Medicinal Chemistry letters, 1997, vol. 7, No. 8, pp. 955-960.
Sivolapenko, et.al. “Imaging of metastic melanoma utilising a technetium-99m labelled RGD-containing synthetic peptide” European Journal of Nucelar Medicine 1998, vol. 25, No. 10, pp. 1383-1389.
Uehara, et.al. “The integrity of the disulfide bond in a cyclic somatostatin analog during 99mTc complexation reactions” Nuclear Medicine & biology, 1999, vol. 26, pp. 883-890.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Peptide-based compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Peptide-based compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptide-based compounds will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2708146

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.