Peptide antibodies and their use in detecting oncogene products

Details Peptide antibodies and their use in detecting oncogene products Peptide antibodies and their use in detecting oncogene products

1984-10-17

1988-08-09

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Lymphokine

A61K 39395

Patent

active

047627069

ABSTRACT:
Antibodies exhibit specificity toward single amino acid differences between proteins. These antibodies may be produced by synthesizing a peptide of the appropriate amino acid sequence contained in the protein, immunizing a host with the peptide, and extracting sera from the host to obtain the antibodies. The antibodies and the desired protein are then immunoprecipitated under conditions of partial denaturation to expose the epitope of the protein. The antibodies may be used for diagnostic or therapeutic purposes.

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