Peptide antibiotics

Details Peptide antibiotics Peptide antibiotics

1989-02-13

1990-02-06

Bond, Robert T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

530317, C07D24102

Patent

active

048989401

ABSTRACT:
Novel peptides of the formula ##STR1## wherein R is CH.sub.3 --(CH.sub.2).sub.6, CH.sub.3 --(CH.sub.2).sub.4 --CH.dbd.CH--(CH.sub.2).sub.2 and CH.sub.3 (CH.sub.2).sub.8 having antibiotic and antitumor activity are prepared by cultivation of the novel microorganism Polyangium brachysporum. Enzymatic hydrolysis of those peptides gives other peptides usfeul as intermediates in the preparation of peptides having activity as antibiotics and/or antitumor agents.

REFERENCES:
patent: 4892510 (1987-09-01), Konishi et al.

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