Peptide antagonists of zonulin and methods for use of the same

Details Peptide antagonists of zonulin and methods for use of the same Peptide antagonists of zonulin and methods for use of the same

2005-08-30

2005-08-30

Weber, Jon (Department: 1653)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

8 to 10 amino acid residues in defined sequence

Reexamination Certificate

active

06936689

ABSTRACT:
Peptide antagonists of zonulin are disclosed, as well as methods for the use of the same. The peptide antagonists bind to the zonula occludens receptor, yet do not physiologically modulate the opening of mammalian tight junctions.

REFERENCES:
patent: 5945510 (1999-08-01), Fasano
patent: 0 557 897 (1993-09-01), None
patent: 0 675 199 (1995-10-01), None
patent: WO 94/11509 (1994-05-01), None
Baudry et al,Infect. Immun., 60(2):428-434 (1992).

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